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PUBLIC RELEASE DATE:
1-Aug-2014

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Contact: Katelyn McCarthy
katelyn.mccarthy@uhhospitals.org
216-767-8582
University Hospitals Case Medical Center
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New research characterizes in-flight pediatric deaths

Researchers find lap infants at increased risk

CLEVELAND, Ohio In a first-of-its-kind study, researchers at University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) found that lap infants may be at greater risk for death on a commercial airline flight. The study analyzed pediatric medical emergencies on flights worldwide between January 2010 and June 2013 and found 90 percent of deaths occurred in children under the age of 2.

The study was conducted in partnership with MedAire to characterize the rare event of an in-flight pediatric fatality onboard commercial airline flights worldwide. Through a detailed analysis of more than 7,000 reported medical emergencies involving children (newborn to age 18) over a three-year period, researchers found death most commonly occurred in previously healthy children under the age of 2, and in children with a preexisting medical condition.

"The pattern we identified in our analysis is intriguing and could indicate lap infants are at greater risk of death related to in-flight environmental factors such as sleeping arrangements," says Alexandre Rotta, MD, FCCM, Chief, Division of Pediatric Critical Care Medicine at UH Rainbow and the studies' principal investigator. Dr. Rotta, who is also Professor of Pediatrics at Case Western Reserve University School of Medicine, says the pattern would have gone unnoticed through single case analysis of these relatively rare events.

The fatalities were identified by searching records of all in-flight medical emergencies for child passengers that were reported to MedAire, the world's busiest global emergency response center and the leading provider of ground-based medical support to commercial airlines worldwide. Of the 7,573 reported emergencies, 10 resulted in death, and six had no previous medical history. Four passengers had preflight medical conditions, including two children traveling for the purpose of accessing advanced medical care. Dr. Rotta speculates these infants were at increased risk from exposure to a hypoxic cabin environment, or by sharing a seat with an adult and co-sleeping during a long flight, but there could also be another yet unknown factor.

The majority of pediatric in-flight emergencies are related to infections, neurological conditions, and respiratory issues such as asthma, seldom require alteration of flight route and do not pose significant risk to life. Because an in-flight pediatric death is such a rare event, large datasets were necessary to capture a meaningful number of observations.

"I hope our findings lead to further research on this important subject," says Dr. Rotta. "It is my belief the pattern we discovered should promote the development of preventative strategies and travel policies to protect the health of all pediatric airplane passengers, especially infants."

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The study published today, ahead of print, in the Pediatric Critical Care Medicine Journal: http://journals.lww.com/pccmjournal/Abstract/publishahead/Fatalities_Above_30

About University Hospitals Rainbow Babies & Children's Hospital

Located on the campus of University Hospitals Case Medical Center in Cleveland, Ohio, University Hospitals Rainbow Babies & Children's Hospital is a 244-bed, full-service children's hospital and academic medical center dedicated to the health care needs of children. A trusted leader in children's health care for more than 125 years, UH Rainbow Babies & Children's Hospital consistently ranks among the top children's hospitals in the nation. As the region's premier resource for pediatric referrals, UH Rainbow Babies & Children's Hospital's dedicated team of more than 1,300 pediatric specialists uses the most advanced treatments and latest innovations to deliver the complete range of pediatric specialty services for more than 700,000 patient encounters each year. Learn more at RainbowBabies.org.

Among the nation's leading academic medical centers, UH Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a nationally recognized leader in medical research and education.



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