Public Release: 

Genomics studies assess childhood, young adulthood cancers

The JAMA Network Journals

Genomics assessments of childhood and young adulthood cancers are the subject of two new studies, an editorial and an author audio interview published online by JAMA Oncology.

In the first study, Katherine A. Janeway, M.D., M.Sc., of the Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, and coauthors assessed the feasibility of identifying actionable genetic alterations and making individualized cancer therapy recommendations in pediatric patients with extracranial solid tumors.

In the second study, D. Williams Parsons, M.D., Ph.D., and Sharon E. Plon, M.D., Ph.D., of the Texas Children's Cancer Center and Baylor College of Medicine, Houston, characterized the diagnostic yield of combined tumor and germline whole-exome sequencing for children with solid tumors.

To read the full studies and a related editorial by Javed Khan, M.D., and Lee J. Helman, M.D., of the National Cancer Institute, Bethesda, Md., please visit the For The Media website.

An author audio interview also is available for preview on the For The Media website. The author audio interview will be live on the JAMA Oncology website when the embargo lifts. Janeway et al (JAMA Oncol. Published online January 28, 2016. doi:10.1001/jamaoncol.2015.5689. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: The study includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Parsons et al (JAMA Oncol. Published online January 28, 2016. doi:10.1001/jamaoncol.2015.5699. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: The study includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Related Content from JAMA: Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

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Media Advisory: To contact corresponding study author Katherine A. Janeway, M.D., M.Sc., call Anne Doerr at 617-632-5665 or email anne_doerr@dfci.harvard.edu. To contact corresponding study author D. Williams Parsons, M.D., Ph.D., or Sharon Plon, M.D., Ph.D., call Dana Benson at 713-798-8267 or email benson@bcm.edu. To contact editorial corresponding author Javed Khan, M.D., call NCI Press Officers at 301-496-6641 or email ncipressofficers@mail.nih.gov.

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