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Showing releases 126-150 out of 572.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

Public Release: 20-Nov-2014
PLOS Neglected Tropical Diseases
Breakthrough in managing yellow fever disease
Found in South America and sub-Saharan Africa, each year yellow fever results in 200,000 new cases and kills 30,000 people. About 900 million people are at risk of contracting the disease. Now a research team led by a biomedical scientist at UC Riverside has determined that the yellow fever virus, a hemorrhagic fever virus, replicates primarily in the liver; other organ failures that often follow in people with the disease are due to secondary effects.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 20-Nov-2014
Cell Reports
Salk scientists unveil powerful method to speed cancer drug discovery
The new method lets researchers identify weak and previously undetectable interactions between proteins inside living cells.

Contact: Salk Communications
press@salk.edu
Salk Institute

Public Release: 20-Nov-2014
Cell Reports
Signaling molecule crucial to stem cell reprogramming
While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments.
California Institute for Regenerative Medicine, National Institutes of Health, UC San Diego Stem Cell Program, NIH/National Institute of Child Health and Human Development

Contact: Scott LaFee
slafee@ucsd.edu
619-543-5232
University of California - San Diego

Public Release: 20-Nov-2014
Journal of Health and Social Behavior
Job authority increases depression symptoms in women, decreases them in men
A new study finds that having job authority increases symptoms of depression among women, but decreases them among men.
NIH/National Institute on Aging

Contact: Daniel Fowler
pubinfo@asanet.org
202-527-7885
American Sociological Association

Public Release: 20-Nov-2014
American Journal of Respiratory Cell and Molecular Biology
Fat a culprit in fibrotic lung damage
Researchers debate whether the lung tissue in pulmonary fibrosis is directly damaged, or whether immune cells initiate the scarring process -- an important distinction when trying to find ways to battle the disease. Now research shows that both processes may be important, and suggest a new direction for developing therapies.

Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University

Public Release: 20-Nov-2014
Chemistry & Biology
Researchers report way to target hard-to-hit site in disease pathway
Researchers have successfully targeted an important molecular pathway that fuels a variety of cancers and related developmental syndromes called 'Rasopathies.' Reporting their results Nov. 20 in Chemistry & Biology, scientists at Cincinnati Children's Hospital Medical Center say they identified a class of lead compounds that successfully recognize a key target in the Ras signaling pathway -- opening the door to future development of therapies that could make treatments more effective with fewer side effects.
National Institutes of Health

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 20-Nov-2014
Nature Communications
Serotonin's early role in the assembly of brain circuits
During the development of the cortex, different kinds of neurons must migrate to attain their final destinations, before forming the essential neural circuits necessary for good cognitive and emotional function. But early dysregulation in the serotonin system has been associated with a higher risk of developing psychiatric problems. Researchers at the University of Geneva have discovered the crucial role of a serotonin receptor in this phenomenon.

Contact: Alexandre Dayer
alexandre.dayer@unige.ch
41-223-795-386
Université de Genève

Public Release: 20-Nov-2014
PLOS Neglected Tropical Diseases
Breakthrough in managing yellow fever disease
Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Found in South America and sub-Saharan Africa, each year the disease results in 200,000 new cases and kills 30,000 people. About 900 million people are at risk of contracting the disease.
National Institutes of Health

Contact: Lauren Bullen
plosntds@plos.org
415-590-3548
PLOS

Public Release: 20-Nov-2014
Clinical Journal of the American Society of Nephrology
Exercise may improve physical function, lessen pain in patients with kidney disease
A 12-week course of aerobic exercise improved physical function and quality of life in patients with advanced chronic kidney disease. The exercise program also decreased patients' pain.

Contact: Tracy Hampton
thampton@nasw.org
American Society of Nephrology

Public Release: 20-Nov-2014
Journal of the American Society of Nephrology
US policy that gives priority to prior organ donors who need a transplant is working
Living organ donors who later need kidney transplants have much shorter waiting times, and they receive higher quality kidneys compared with similar people on the waiting list who were not organ donors.

Contact: Tracy Hampton
thampton@nasw.org
American Society of Nephrology

Public Release: 20-Nov-2014
PLOS Computational Biology
Epidemic spreading and neurodegenerative progression
Researchers from the Montreal Neurological Institute have used a model inspired by patterns of epidemic disease spreading to map how misfolded proteins propagate within the brain.

Contact: Yasser Iturria-Medina
iturria.medina@gmail.com
514-398-6447
PLOS

Public Release: 20-Nov-2014
PLOS Pathogens
An Ebola virus protein can cause massive inflammation and leaky blood vessels
Ebola GP protein covers the virus' surface and is shed from infected cells during infection. A study published on Nov. 20 in PLOS Pathogens reports that shed GP can trigger massive dysregulation of the immune response and affect the permeability of blood vessels

Contact: Viktor Volchkov
viktor.volchkov@inserm.fr
PLOS

Public Release: 20-Nov-2014
Neuron
Brain training using sounds can help aging brain ignore distractions
As we age, we have an increasingly harder time ignoring distractions. But new research online Nov. 20 in the Cell Press journal Neuron reveals that by learning to make discriminations of a sound amidst progressively more disruptive distractions, we can diminish our distractibility. A similar strategy might also help children with attention deficits or individuals with other mental challenges.

Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press

Public Release: 20-Nov-2014
Stem Cell Reports
Reprogramming 'support cells' into neurons could repair injured adult brains
The cerebral cortex lacks the ability to replace neurons that die as a result of Alzheimer's, stroke, and other devastating diseases. A new study shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice. The findings reveal that NG2 glia represent a promising target for neuronal cell replacement strategies to treat brain injury.

Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press

Public Release: 20-Nov-2014
Immunity
Immune cells from the spleen found to control chronic high blood pressure
High blood pressure is a leading cause of death around the world, and its prevalence continues to rise. A new Immunity study shows that a protein in the spleen called placental growth factor plays a critical role in activating a harmful immune response that leads to the onset of high blood pressure in mice. The findings pave the way for the development of more effective treatments for this common and deadly condition.

Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press

Public Release: 20-Nov-2014
Science
Staying ahead of the game: Pre-empting flu evolution may make for better vaccines
An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by 'pre-empting' the evolution of the influenza virus.
National Institutes of Health

Contact: Craig Brierley
craig.brierley@admin.cam.ac.uk
44-012-237-66205
University of Cambridge

Public Release: 19-Nov-2014
Small
NTU Singapore develops novel 2-in-1 biomarker and drug delivery system
Nanyang Technological University has invented a unique biomarker with two exceptional functions.

Contact: Lester Kok
lesterkok@ntu.edu.sg
Nanyang Technological University

Public Release: 19-Nov-2014
New England Journal of Medicine
Gene therapy provides safe, long-term relief for patients with severe hemophilia B
Gene therapy developed at St. Jude Children's Research Hospital, University College London and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported. The results appear in the Nov. 20 edition of the New England Journal of Medicine.
NIH/National Heart, Lung, and Blood Institute, Assisi Foundation of Memphis, Howard Hughes Medical Institute, ALSAC, Medical Research Council, Katharine Dormandy Trust, NHS Blood and Transplant, and others

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 19-Nov-2014
Journal of Biological Chemistry
Researchers identify protein mutation that alters tissue development in males before birth
Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. The findings appear in the Nov. 21 edition of the Journal of Biological Chemistry, whose editors named the article its Paper of the Week.
National Institutes of Health

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 19-Nov-2014
Nature
Major new study reveals new similarities and differences between mice and humans
Powerful clues have been discovered about why the human immune system, metabolism, stress response, and other life functions are so different from those of the mouse. A new, comprehensive study of the mouse genome by an international team reveals striking similarities and differences with the human genome. The study may lead to better use of mouse models in medical research.
NIH/National Human Genome Research Institute

Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State

Public Release: 19-Nov-2014
American Public Works Association Western Snow and Ice Conference
Cut the salt: Green solutions for highway snow and ice control
Ice-free pavement. 'Smart snowplows.' Vegetable juice ice-melt. Cold-climate researchers at Washington State University are clearing the road with green alternatives to the salt, sand and chemicals typically used for highway snow and ice control.

Contact: Xianming Shi
Xianming.shi@wsu.edu
509-335-7088
Washington State University

Public Release: 19-Nov-2014
New England Journal of Medicine
MSK team makes key discovery in understanding immunotherapy's successes -- and its failures
A collaborative team of leaders in the field of cancer immunology from Memorial Sloan Kettering Cancer Center has made a key discovery that advances the understanding of why some patients respond to ipilimumab, an immunotherapy drug, while others do not.
Ludwig Cancer Research, Frederick Adler Fund, National Institutes of Health, Swim Across America, Ludwig Trust, Melanoma Research Alliance, Stand Up To Cancer-Cancer Research Institute Immunotherapy Dream Team

Contact: Jeanne D'Agostino
dagostij@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center

Public Release: 19-Nov-2014
Association for the Study of Higher Education Annual Meeting
Professional majors strengthen the mission of liberal arts colleges
University of Iowa study finds small liberal arts colleges that add professional and vocational majors strengthen their mission, not weaken it.
Center of Inquiry in the Liberal Arts at Wabash College

Contact: Sara Agnew
sara-agnew@uiowa.edu
319-384-0073
University of Iowa

Public Release: 19-Nov-2014
Nature Climate Change
Climate change will slow China's progress in reducing infectioius diseases
A new study found that by 2030, changes to the global climate could delay China's progress reducing diarrheal and vector-borne diseases by up to seven years.

Contact: Melva Robertson
melva.robertson@emory.edu
404-727-5692
Emory Health Sciences

Public Release: 19-Nov-2014
American Heart Association's Scientific Sessions 2014
Delivering stem cells into heart muscle may enhance cardiac repair and reverse injury
Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue, according to a study led by researchers from Icahn School of Medicine at Mount Sinai.

Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Showing releases 126-150 out of 572.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>