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Showing releases 351-371 out of 371.

<< < 10 | 11 | 12 | 13 | 14 | 15

Public Release: 25-Sep-2014
American Journal of Human Genetics
Large study pinpoints synapse genes with major roles in severe childhood epilepsies
An international research team has identified gene mutations causing severe, difficult-to-treat forms of childhood epilepsy. Many of the mutations disrupt functioning in the synapse, the highly dynamic junction at which nerve cells communicate with one another.
National Institutes of Health, European Science Foundation, The Andrew's Foundation

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 25-Sep-2014
Cell Reports
New protein players found in key disease-related metabolic pathway
Cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway -- which senses the availability of nutrients -- to coordinate their growth with existing environmental conditions. The lab of Whitehead Member David Sabatini has identified a family of proteins that negatively regulate the branch upstream of mTORC1 that senses amino acids, the building blocks of proteins. The mTORC1 pathway is known to be deregulated in a variety of diseases, including diabetes, epilepsy, and cancer.
National Institutes of Health, Department of Defense

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 25-Sep-2014
Science
Agonizing rabies deaths can be stopped worldwide
In the current issue of Science magazine, an international team of researchers led by the Paul G. Allen School for Global Animal Health at Washington State University report that ridding the world of rabies in humans is cost-effective and achievable through mass dog vaccination programs.
Paul G. Allen School for Global Animal Health, Lincoln Park Zoological Society, MSD Animal Health, Tusk Trust

Contact: Guy Palmer, Ph.D
gpalmer@wsu.edu
509-432-3385
Washington State University

Public Release: 25-Sep-2014
Cell
Strategic or random? How the brain chooses
Many of the choices we make are informed by experiences we've had in the past. But occasionally we're better off abandoning those lessons and exploring a new situation unfettered by past experiences. Scientists at the Howard Hughes Medical Institute's Janelia Research Campus have shown that the brain can temporarily disconnect information about past experience from decision-making circuits, thereby triggering random behavior.

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute

Public Release: 25-Sep-2014
Lancet Psychiatry
Talk therapy -- not medication -- best for social anxiety disorder, large study finds
While antidepressants are the most commonly used treatment for social anxiety disorder, new research suggests that cognitive behavioral therapy is more effective and, unlike medication, can have lasting effects long after treatment has stopped.
National Institute for Health and Care Excellence

Contact: Stephanie Desmon
sdesmon1@jhu.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health

Public Release: 25-Sep-2014
Nature Communications
Live long and phosphor: Blue LED breakthrough for efficient electronics
In a step that could lead to longer battery life in smartphones and lower power consumption for large-screen televisions, researchers at the University of Michigan have extended the lifetime of blue organic light emitting diodes by a factor of 10.
Universal Display

Contact: Kate McAlpine
kmca@umich.edu
734-763-4386
University of Michigan

Public Release: 25-Sep-2014
Current Biology
Dinosaur family tree gives fresh insight into rapid rise of birds
The most comprehensive family tree of meat-eating dinosaurs ever created is enabling scientists to discover key details of how birds evolved from them.
European Commission, National Science Foundation, University of Edinburgh, Columbia University, American Museum of Natural History, Swarthmore College/Research Fund, James Michener Faculty Fellowship

Contact: Corin Campbell
Corin.Campbell@ed.ac.uk
44-131-650-2246
University of Edinburgh

Public Release: 25-Sep-2014
A galaxy of deception
Astronomers usually have to peer very far into the distance to see back in time, and view the Universe as it was when it was young. This new NASA/ESA Hubble Space Telescope image of galaxy DDO 68, otherwise known as UGC 5340, was thought to offer an exception. This ragged collection of stars and gas clouds looks at first glance like a recently-formed galaxy in our own cosmic neighborhood. But, is it really as young as it looks?

Contact: Georgia Bladon
gbladon@partner.eso.org
49-893-200-6855
ESA/Hubble Information Centre

Public Release: 25-Sep-2014
Stem Cell Research & Therapy
Turmeric compound boosts regeneration of brain stem cells
A bioactive compound found in turmeric promotes stem cell proliferation and differentiation in the brain, reveals new research published today in the open access journal Stem Cell Research & Therapy. The findings suggest aromatic turmerone could be a future drug candidate for treating neurological disorders, such as stroke and Alzheimer's disease.

Contact: Alanna Orpen
alanna.orpen@biomedcentral.com
44-020-319-22054
BioMed Central

Public Release: 25-Sep-2014
Cell Reports
Novel compound prevents metastasis of multiple myeloma in mouse studies
Dana-Farber scientists and colleagues find the compound olaptesed pegol can stop multiple myeloma from spreading in mouse models, potentially leading to a new approach in addressing the challenge of metastasis, one of the deadliest aspects of cancer.
NIH/National Cancer Institue

Contact: Teresa M Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute

Public Release: 25-Sep-2014
Molecular Cell
Super enhancers in the inflamed endothelium
A study led by researchers at Brigham and Women's Hospital and Dana-Farber Cancer Institute is the first to demonstrate that BET bromodomain-containing proteins help execute this global inflammatory program in the endothelium while BET bromodomain inhibition can significantly decrease atherosclerosis in vivo.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 25-Sep-2014
Science
Earth's water is older than the sun
Water was crucial to the rise of life on Earth and is also important to evaluating the possibility of life on other planets. Identifying the original source of Earth's water is key to understanding how life-fostering environments come into being and how likely they are to be found elsewhere. New work found that much of our solar system's water likely originated as ices that formed in interstellar space.

Contact: Conel Alexander
calexander@carnegiescience.edu
Carnegie Institution

Public Release: 25-Sep-2014
Current Biology
Brain chemical potential new hope in controlling Tourette Syndrome tics
A chemical in the brain plays a vital role in controlling the involuntary movements and vocal tics associated with Tourette Syndrome, a new study has shown.

Contact: Emma Thorne
emma.thorne@nottingham.ac.uk
44-011-595-15793
University of Nottingham

Public Release: 25-Sep-2014
Cell
How physical exercise protects the brain from stress-induced depression
Physical exercise has many beneficial effects on human health, including the protection from stress-induced depression. However, until now the mechanisms that mediate this protective effect have been unknown. In a new study in mice, published in Cell, Swedish researchers show that exercise training induces changes in skeletal muscle that can purge the blood of a substance that accumulates during stress, and is harmful to the brain.
AstraZeneca-Karolinska Institutet Integrated Translational Research Centre, Novo Nordisk Foundation, Petrus and Augusta Hedlund Foundation, Stockholm County Council, Karolinska Institutet Strategic Research Programme in Diabetes

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 25-Sep-2014
Science
Stone Age site challenges old archaeological assumptions about human technology
Analysis of stone artifacts from the excavation of a 300,000 year old site in Armenia shows that new technologies evolved locally, rather than being imported from outside, as previously thought.
University of Connecticut, UK Natural Environment Research Council, L.S.B. Leakey Foundation, Irish Research Council, University of Winchester, UK

Contact: Tim Miller
tim.miller@uconn.edu
860-486-4064
University of Connecticut

Public Release: 25-Sep-2014
Journal of the American Society of Nephrology
Viral infection in transplant recipients increases risk of developing damaging antibodies
Among kidney transplant recipients, persistent infection with BK virus does not have a negative immediate-term impact on patient or kidney survival, but infected patients are more likely to develop antibodies against their kidney transplants. Such donor-specific antibodies are known to be detrimental to the survival of transplanted organs.

Contact: Tracy Hampton
thampton@nasw.org
American Society of Nephrology

Public Release: 25-Sep-2014
Science
Interstellar molecules are branching out
Scientists from the Max Planck Institute for Radio Astronomy, Cornell University and the University of Cologne have for the first time detected a carbon-bearing molecule with a 'branched' structure in interstellar space.

Contact: Dr. Arnaud Belloche
belloche@mpifr-bonn.mpg.de
49-022-852-5376
Max-Planck-Gesellschaft

Public Release: 25-Sep-2014
Cell
Modified vitamin D shows promise as treatment for pancreatic cancer
Salk scientists find that a vitamin D-derivative makes tumors vulnerable to chemotherapy.

Contact: Salk Communications
press@salk.edu
Salk Institute

Public Release: 25-Sep-2014
Current Biology
How the brain gains control over Tourette syndrome
Tourette syndrome is a developmental disorder characterized by involuntary, repetitive, and stereotyped movements or utterances. Now researchers have new evidence to explain how those with Tourette syndrome in childhood often manage to gain control over those tics. In individuals with the condition, a portion of the brain involved in planning and executing movements shows an unusual increase compared to the average brain in the production of a primary inhibitory neurotransmitter known as GABA.

Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press

Public Release: 25-Sep-2014
Cell
In the face of uncertainty, the brain chooses randomness as the best strategy
A new study shows that, in competitive situations, rats abandon their normal tactic of using past experience to make decisions and instead make random choices when their competitor is hard to defeat. This switch in strategy is controlled by a brain circuit, indicating that the brain can enter a random decision-making mode when it provides a competitive edge. These findings may have implications for human disorders, in which even ordinary decision-making is viewed as ineffective.

Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press

Public Release: 25-Sep-2014
PLOS Pathogens
Stem cell transplant does not cure SHIV/AIDS after irradiation of infected rhesus macaques
A study published on Sept. 25 in PLOS Pathogens reports a new primate model to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the 'Berlin patient,' the only human thought to have been cured so far.

Contact: Guido Silvestri
gsilves@emory.edu
404-727-9139
PLOS

Showing releases 351-371 out of 371.

<< < 10 | 11 | 12 | 13 | 14 | 15