Women who go on to develop type 2 diabetes after having gestational, or pregnancy-related, diabetes are more likely to have particular genetic profiles, suggests an analysis by researchers at the National Institutes of Health and other institutions. The findings provide insight into the genetic factors underlying the risk of type 2 diabetes and may inform strategies for reducing this risk among women who had gestational diabetes.
The hormone kisspeptin can enhance brain activity associated with attraction, according to a new study.
Skeletal muscle mass and strength are critical in helping prevent falls, fractures, and disability. Yet, they continue to decline during the menopause transition. A new study showed that the prolonged use (defined as ≥13 mo) of hormone therapy (HT) was associated with higher muscle mass and less chance of sarcopenia. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Lumbar disc degeneration and resulting lower back pain become greater concerns with age and disproportionately affect women more than men, likely as a result of decreasing estrogen levels during menopause. A new study demonstrates that vitamin D deficiency, smoking, high body mass index (BMI), and osteoporosis are risk factors for greater back pain. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells -- the cells in the pancreas that produce insulin. The result is an important step toward a diabetes treatment that restores the body's ability to produce insulin.
Having genetically higher testosterone levels increases the risk of metabolic diseases such as type 2 diabetes in women, while reducing the risk in men. Higher testosterone levels also increase the risks of breast and endometrial cancers in women, and prostate cancer in men.
Idiopathic ketotic hypoglycemia (IKH) is often relatively mild and may remain undiagnosed. Luckily it often disappears with age. But severe variants, sometimes affecting several family members, have prompted the research team at the Complex Hypoglycemia Center, Odense University Hospital, Denmark, to dive more deeply into potential new genetic explanations for this disease. -We have identified four novel genes that appear to explain the IKH in at least four families, researchers say.
Mindfulness-based therapy may help reduce stress, appetite and body weight in children with obesity and anxiety, according to a study published in Endocrine Connections. They reported that obese children on a calorie-restricted diet alongside mindfulness therapy lose more weight and are less stressed and hungry, than children on a calorie-restricted diet alone.
Treatment with a naturally occurring antioxidant, CoQ10, restores many aspects of fertility in C. elegans worms following exposure to BPA Findings offer possible path toward undoing BPA-induced reproductive harms in people Although CoQ10 is available over the counter, it is not yet clear whether the compound could improve human fertility or do so safely
Hormone therapy has proven to slow down heart fat deposition and the progression of atherosclerosis, depending on the type of hormone therapy and route of administration. A new study compared the effects of conjugated equine estrogens (CEE) and 17β-estradiol and contrasted oral and transdermal delivery to determine their effectiveness in preventing heart disease. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).