Cellular energy metabolism also follows the rhythm of the circadian clock. A University of Basel study has now shown exactly how this works by revealing the relationship between the circadian rhythm and the mitochondrial network for the first time.
A new study from University of Colorado Boulder found that preschoolers exposed to bright light at bedtime had an 88 percent reduction in melatonin levels. Anatomical differences in their young eyes may make them more vulnerable to adverse impacts of bright light, the researchers say.
Circadian clocks arose as an adaptation to dramatic swings in daylight hours and temperature caused by the Earth's rotation, but we still don't fully understand how they work. During the 62nd Biophysical Society Meeting, held Feb. 17-21, Andy LiWang, University of California, Merced, will present his lab's work studying the circadian clock of blue-green colored cyanobacteria. LiWang's group discovered that how the proteins move hour by hour is central to cyanobacteria's circadian clock function.
A new study takes a deep look at the connection between shift work and type 2 diabetes. Investigators at Brigham and Women's Hospital leveraged data on hundreds of thousands of people in the UK Biobank to better understand how shift work -- especially frequent night work -- contributes to the likelihood of type 2 diabetes. The team also developed a genetic risk score for type 2 diabetes, examining genetic data for tens of thousands of workers in the database.
Salk scientists discover critical gene activity follows a biological clock, affecting diseases of the brain and body.
People with Alzheimer's disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers at Washington University School of Medicine in St. Louis have found that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer's.
Extended shift work has historically been linked to interrupted sleep patterns and risk of injury, and is a persistent problem for emergency medical services (EMS) personnel who are tasked with delivering acute care under significant pressure. New guidelines, written by a team led by University of Pittsburgh School of Medicine scientists aim to mitigate the effects of fatigue by addressing the impact of shift work and scheduling.
We may have a new reason, in addition to vitamin D generation, to bask in a little sunshine. A breakthrough study by UAlberta researchers has shown the fat cells that lie just beneath our skin shrink when exposed to the blue light emitted by the sun.
Biological clocks throughout the body play a major role in human health and performance, from sleep and energy use to how food is metabolized and even stroke severity. Now, Texas A&M University researchers found that circadian rhythms could hold the key to novel therapies for glioblastoma, the most prevalent type of brain cancer in adults -- and one with a grim prognosis.
Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells' access to certain nutrients.