Scientists have made a step forward in understanding the evolution of human feet.
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions. A research team led by Dongsheng Duan, PhD, at the University of Missouri School of Medicine has identified and overcome a barrier in CRISPR gene editing that may lay the foundation for sustained treatments using the technique.
There is an ongoing debate regarding the relationship between knee osteoarthritis and hormone therapy (HT), with small-scale studies providing mixed results. A new large-scale study from Korea shows that women receiving HT had a significantly lower prevalence of symptomatic knee osteoarthritis compared with women who did not take hormones. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).
Children with life-threatening respiratory failure who require mechanical ventilation in a pediatric intensive care unit commonly experience rapid muscle atrophy, according to a study published online Dec. 19, 2018, in PLOS ONE.
Working with nine animal models, researchers find a preference for stability over energy conservation during speed-related gait transitions.
The use of early physical therapy in a study of nearly 89,000 US adults with musculoskeletal pain of the shoulder, neck, knee and low back was associated with a lower likelihood of subsequent opioid use in an analysis of health insurance claims from 2007 to 2015. For patients who did use opioids, early physical therapy was associated with reduced opioid use for shoulder, knee and low back pain but not neck pain.
A recent experimental study conducted by researchers at the University of Illinois at Urbana-Champaign, Washington University in St. Louis, and Columbia University on nanoscale collagen fibrils reported on, previously unforeseen, reasons why collagen is such a resilient material.
Patients with arthritis in their knees experienced significant improvement in pain and mobility after undergoing a weekly, whole-body massage for two months, according to a study led by researchers at Duke Health.
To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion of stem cells into muscle. Findings appeared in Cell Reports.
A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.