The CHD8 gene is associated with some cases of human autism. A new study shows that mice with mutated CHD8 show defects in brain development and behavioral changes, and may give insight into genetic causes of autism spectrum disorders.
The heart is a dynamic muscle that grows and shrinks in response to stressors such as exercise and disease. The secret to its malleability lies in individual cells, which get bigger or smaller depending on the heart's needs. A new study of mouse hearts reveals a previously unknown mechanism by which heart cells control their size by ramping up or stopping the production of a key factor called PABPC1.
Researchers have now discovered a new mobile colistin resistance gene, mcr-3, in E. coli of pig origin. The novel mcr-3 gene was discovered when a colistin-resistant Escherichia coli isolate tested negative for both mcr-1 and mcr-2. This novel mobile colistin resistance gene may already be widely disseminated. Screening for the mcr-3 gene should be urgently included in the surveillance of colistin-resistant Gram-negative pathogens from animals, humans, and the environment.
The silver nanowires are held together in the polymer so that they touch, and as long as the polymer doesn't dissolve, the nanowires will form a path to conduct electricity similar to the traces on a circuit board.
Scientists at the Morgridge Institute for Research at the University of Wisconsin-Madison have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.
But the woodrats' unique adaptation that allows them to break down creosote toxins may be in jeopardy if temperatures continue to rise, according to University of Utah researchers. Their new study in Molecular Ecology explains why: Livers of mammals (including us) may be less efficient at breaking down toxins at higher temperatures.
Scientists at the University of Konstanz and Umea University in Sweden have arrived at a structural model of the enzyme adenylate kinase in its closed state
Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells. The research uses pioneering cryo-electron tomography to reveal the complex viral replication process in vivid detail, opening up new avenues to potentially disrupt, dismantle or redirect viral machinery.
Under anaerobic conditions, certain bacteria can produce electricity. This behavior can be exploited in microbial fuel cells, with a special focus on wastewater treatment schemes. A weak point is the dissatisfactory power density of the microbial cells. An unconventional solution is now presented by Singaporean and Chinese scientists: as reported in the journal Angewandte Chemie, they coated live, electroactive bacteria with a conducting polymer and obtained a high-performance anode for microbial fuel cells.
The intensive management of grasslands is bad for biodiversity. However, a study by the Terrestrial Ecology Research Group at the Technical University of Munich (TUM) has brought a ray of hope: If different forms of management are optimally distributed within a region, this can lead to higher yields without the loss of insect species. In ideal cases, this will allow even more species to find habitats that are optimal for them. What is crucial here is that management is planned at the landscape level.