Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting. Researchers at Texas A&M University have now created superior bone grafts using primitive stem cells. They found that these cells help create very fertile scaffolds needed for bone to regenerate at the site of repair.
Scientists from Nanjing University and University of Macau have transformed the spleen into a functioning liver in living mice, which could bring new hope for patients suffering from organ shortage worldwide.
University of Colorado Denver researchers are the first to 3D print a complex, porous lattice structure using liquid crystal elastomers creating devices that can mimic cartilage and other biological tissues.
For the first time, growing human skin cell capable of growing hair embedded with fat and nerve cells is a reality. The platform could have applications for testing cosmetics, drugs, and burn treatments along with creating other cultured human organ models, including the inner ear.
Prior studies suggested women might have higher mortality of cirrhosis of the liver than men. Women are also less likely to receive liver transplantation. But the research was unclear. A comprehensive new Northwestern Medicine study shows women are not more likely to die of liver cirrhosis than men, demonstrating that this liver disease affects men and women similarly.
Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats. In this proof-of-concept experiment, the lab-made organs survived for four days inside their animal hosts.
A recent study from the Mechanobiology Institute at the National University of Singapore has shown that rejuvenated fibroblasts can recover their ability to self-contract. This encouraging discovery holds great potential for applications in regenerative medicine and stem cell engineering.
High-throughput platform identifies complex conditions with biomaterial compositions, and mechanical and chemical stimuli that help stem cells produce more robust cartilage.
This observational study looked at the disparities that exist between women and men waiting to receive a liver transplant, such as being more likely to die while on the wait list, and how much these differences are associated with factors including geographic location, medical urgency and liver size.
The characteristics, treatment and outcomes of heart transplant recipients who were infected with COVID-19 in New York City are described in this case series.