Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy were studied in multiple model organisms. An Osaka University-led research team found that Rubicon suppression led to reduction of age-associated motor decline, as well as reduction of fibrosis, and that Rubicon could be an important new target for treatments designed to reduce the effects of aging in humans.
Many travelers are members of multiple loyalty programs, and the role of these programs is often insignificant when choosing between different hotels, a new study from the University of Eastern Finland shows.
Salk Institute researchers have developed a new gene therapy to help decelerate the aging process. The findings, published on February 18, 2019, in the journal Nature Medicine, highlight a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome, a rare genetic disorder that also afflicts humans.
A new report, developed by the Baker Heart and Diabetes Institute, reveals that prevention of secondary heart attacks and strokes is critical to combating Australia's number one killer -- cardiovascular disease. It highlights the critical and timely opportunity to invest in secondary prevention in Australia.
Excavations at two quarries in Wales, known to be the source of the Stonehenge 'bluestones', provide new evidence of megalith quarrying 5,000 years ago, according to a new UCL-led study.
A new study has found that the longer older women sit or lay down during the course of a day -- and the longer the individual periods of uninterrupted sitting--the greater their risk of cardiovascular diseases such as heart disease and stroke. But reducing their sedentary time by just an hour a day appears to lower the risk of cardiovascular diseases by 12 percent -- and for heart disease alone, by a dramatic 26 percent, the research found.
Researchers have found evidence for humans hunting small mammals in the forests of Sri Lanka at least 45,000 years ago. The researchers discovered remains of such animals, including primates, with evidence of cut-marks and burning at the oldest archaeological site occupied by humans in Sri Lanka, alongside sophisticated bone and stone tools. This is an example of the uniquely human adaptability that allowed H. sapiens to colonize extreme environments apparently untouched by its hominin relatives.
The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report Feb. 19 in the journal Cell Host & Microbe. With age, B cells and the antibodies they secrete acquire fewer mutations that would provide flexible protection against the ever-changing flu virus.
A new study found an association between marijuana dispensaries and increases in rates of crime and disorder in neighborhoods in Denver, Colo., shortly after Colorado commenced legal retail sales of marijuana.
A study published in Psychological Reports showed that after 3.5 months of practicing Transcendental Meditation (TM), most of the 34 tertiary-level students at Maharishi Institute (MI) -- all of whom were initially diagnosed with PTSD by mental health professionals -- went below clinical thresholds as measured by standard assessments. Students also experienced relief from depression. A comparison group from University of Johannesburg (UJ) with the same diagnosis received no treatment and showed no change in their symptoms.