Researchers from the Josep Carreras Leukaemia Research Institute prove that the preclinical implementation of Acute Myeloid Leukaemia immunotherapy, based on CD123-redirected CAR T-cells, affects hematopoiesis, blood cells production, and reconstitution.
Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce. The first data describing this new direction for fighting COVID-19 were published on June XX in the journal Nano Letters.
Plants are some of nature's most extraordinary chemists. Unlike animals, they can't run from predators or pathogens. They can't uproot themselves to spread their seeds. So instead, they manufacture chemicals to make love and war. But how did plants obtain these capabilities? In a new study, scientists explore this question through the evolution of Gardenia jasminoides, sequencing the species' genome and learning how the plant evolved to make crocin, a useful chemical.
Soap bubbles facilitated the pollination of a pear orchard by delivering pollen grains to targeted flowers, demonstrating that this whimsical technique can successfully pollinate fruit-bearing plants. The study, from the Japan Advanced Institute of Science and Technology in Nomi, Japan, and published June 17 in the journal iScience, suggests that soap bubbles may present a low-tech complement to robotic pollination technology designed to supplement the work of vanishing bees.
The study may suggest new strategies to limit virus attacks and prevent or combat diseases like Sars and Covid-19 based on biomedical and engineering principles. The research was conducted by the University of Trento and by the University of Napoli Federico II, in collaboration with researchers at Carnegie Mellon University and at the University of Pittsburgh, in the USA, and with the universities of Palermo and Ferrara, where experiments were carried out
Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting. Researchers at Texas A&M University have now created superior bone grafts using primitive stem cells. They found that these cells help create very fertile scaffolds needed for bone to regenerate at the site of repair.
Purdue University innovators have created a novel wearable patch to provide an improved treatment experience for people with melanoma. The researchers developed a novel wearable patch with fully miniaturized needles, enabling unobtrusive drug delivery through the skin for the management of skin cancers.
Compared to the vast emptiness of open water, land is rife with obstacles and occlusions. By providing prey with spaces to hide and predators with cover for sneak attacks, the habitats possible on land may have helped give rise to planning strategies -- rather than those based on habit -- for many of those animals.
Could remnants of DNA from a now extinct human subspecies known as the Denisovans help boost the immune functions of modern humans? An international study co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and published in the scientific journal PLOS Genetics, represents the first characterizations of genes in the DNA of healthy individuals from geographically and genetically distinct populations in Indonesia.
Researchers from The University of Tokyo developed a novel fiber-shaped hydrogel transplant for the treatment of type 1 diabetes mellitus. They showed that pancreatic cells encapsulated in 1.0-mm-thick hydrogel fibers normalized blood glucose levels in diabetic mice while being protected from foreign body reactions. These findings help facilitate cell-based therapies for type 1 diabetes mellitus.