Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.
Two landmark studies provide unprecedented structural insight into how plant immune receptors are primed -- and then activated -- to provide plants with resistance against microbial pathogens.
Scientists have created a molecule with both strong anti-Zika properties and low toxicity to animal cells.
Iban Ubarretxena, an Ikerbasque Researcher and Director of the Biofisika Institute (CSIC-UPV/EHU), participates in a piece of research that has enabled new inhibitors to be identified and which could be used to develop drugs to combat Parkinson's. The research has been published in the prestigious journal Cell Research.
Tucked away in the noncoding regions of bird DNA, researchers have discovered molecular roots of the loss of flight seen in so many disparate paleognathous birds.
A small peptide produced in the skin of predatory nematodes prevents them from cannibalizing their immediate family members, while they feed upon their close relatives, a new study finds.
Public health officials could soon be able to detect viruses in mosquitoes in the wild much more quickly and easily -- thanks to the insect equivalent of a urine test. A new study in Australia shows that two kinds of commonly used mosquito traps can be readily modified to collect mosquito excreta, or liquid waste droplets, to be tested for signs of viruses.
Scientists aboard Schmidt Ocean Institute's research vessel Falkor recently discovered and explored a hydrothermal field at 2,000 meters depth in the Gulf of California where towering mineral structures serve as biological hotspots for life. These newly discovered geological formations feature upside down 'mirror-like flanges' that act as pooling sites for discharged fluids.
Researchers discover new cell population that can help in regenerative processes.
Increased levels of the hormone auxin usually promote cell growth in various plant tissues. Researchers at IST Austria have now shown that in special areas of the seedling, increased auxin levels trigger a different gene expression pathway leading to growth inhibition. The discovery, published in the journal Nature, helps to explain the formation of the typical bend or so called apical hook that helps the seedling to break through the soil following germination.