New research from Boston Medical Center found that patients experiencing severe COVID-19 symptoms had improved outcomes when administered an Interleukin-6 (IL6ri) inhibitor, sarilumab or tocilizumab, given to mediate severe systemic inflammatory responses. The treatment was more effective when administered earlier in the disease course and reduced mortality rates and the need for intubation.
A new computational tool developed by researchers from Purdue University and MIT could help better determine which drugs should move from animal testing to humans. It could also sooner detect a reason why a drug might fail, guiding how a clinical trial should be set up.
Real-time measurements captured by researchers at the Department of Energy's Oak Ridge National Laboratory provide missing insight into chemical separations to recover cobalt, a critical raw material used to make batteries and magnets for modern technologies. Results published in ACS Applied Materials and Interfaces track the dynamics of molecules designed to grab cobalt from solutions containing a mixture of similar species.
NASA's Aqua satellite took images of the Apple Fire as it continued to spread north across the head of the Mill Creek Canyon, and east into the San Gorgonio Wilderness near San Bernardino, Calif. on Aug. 3, 2020.
A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer's disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain cells metabolize fatty molecules known as lipids.
Mortality rates after treatment of unruptured intracranial aneurysms have substantially decreased in the past decade, according to new findings presented today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting. The study, Trends in Mortality and Morbidity after Treatment of Unruptured Intracranial Aneurysm in the United States, 2006-2016, analyzed data from 21,609 patients in the Nationwide Inpatient Sample (NIS) database across a 10-year period. The research compares two treatments for unruptured intracranial aneurysms: microsurgical clipping and endovascular embolization.
ORNL Story Tips: Pandemic impact, root studies, neutrons confirm, lab on a crystal and modeling fusion.
A new study presented today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting serves as the first prospective validation of the Rapid Arterial Occlusion Evaluation (RACE) scale in accurately identifying a severe clot stroke called a Large Vessel Occlusion (LVO) by U.S.-based EMS personnel in a pre-hospital setting.
Scientists at Huntsman Cancer Institute at the University of Utah report today the development of new models to study molecular characteristics of tumors of the lung and pancreas that are driven by mutations in a gene named NTRK1. The findings were published today in the journal Cell Reports.
Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists at the University of Cambridge and the California Institute of Technology (Caltech). The researchers say this could mean embryos are susceptible to COVID-19 if the mother gets sick, potentially affecting the chances of a successful pregnancy.