Three decades of research on Alzheimer's disease have not produced major treatment advances for patients, says Steven Clarke, UCLA professor of chemistry and biochemistry. He and UCLA colleagues report new insights that may lead to progress in fighting the devastating disease. They discovered beta amyloid has a specific amino acid that can form a kink, like a kink in a garden hose, creating a harmful molecular zipper and leading to the death of neurons.
Edwin Chapman of the Howard Hughes Medical Institute and the University of Wisconsin-Madison reports that halting production of synaptotagmin 17 (syt-17) blocks growth of axons. Equally significant, when cells made more syt-17, axon growth accelerated. A wide range of neurological conditions could benefit from the growth of axons, including spinal cord injuries and some neurodegenerative diseases.
New research by Sussex scientists could be the first step towards developing a blood test to diagnose the most aggressive type of brain tumor, known as glioblastoma.
Using ultrasonic tweezers, live imaging and a micro-mechanical substrate, NYU Tandon researchers found energy patterns in cellular allostasis that could predict the presence of disease.
Every day, people are exposed to myriad chemicals both natural and synthetic, some of which may affect human physical development. Researchers from Boyce Thompson Institute have discovered nacq#1, a natural compound produced by a soil roundworm that dramatically influences time to sexual maturity and lifespan in tiny amounts. Because nacq#1 and its related nuclear receptors are so similar between the worm and humans, miniscule amounts of small molecules could similarly impact human development and lifespan.
Although the literature describes the mammalian zygote as a totipotent cell, one researcher challenges this view and has proposed a revised alternative model of mammalian cellular totipotency.
Burning invasive western juniper increases the time -- post-fire -- that native mountain sagebrush will remain the dominant woody vegetation in the plant community by at least 44 percent compared to cutting juniper back, according to a new study in Ecology and Evolution by Agricultural Research Service (ARS) scientists and their collaborators.
A new Tel Aviv University study finds that melanoma-related brain metastasis occurs when tumor cells 'hijack' an inflammatory pathway in the brain. Blocking this pathway could prevent these metastases from developing, according to the research.
An international team of Russian and Belgian researchers, including scientists from HSE University, has found out that space travel has a significant impact on the brain: they discovered that cosmonauts demonstrate changes in brain connectivity related to perception and movement.
In a recently published study examining the effects of binge drinking on rats, researchers from the University of Missouri School of Medicine discovered that female rats who were of equal age and weight to male rats were more sensitive to alcohol and experienced alcoholic liver injury at a higher rate than male rats.