Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data presented at the San Antonio Breast Cancer Symposium.
Air pollution impairs the function of blood vessels in the lungs, according to a study in more than 16,000 patients presented today at EuroEcho-Imaging 2016.
Neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit and hyperactivity disorder (ADHD) are on the rise but their underlying mechanisms are poorly understood.
University of Tsukaba-led researchers showed that impaired glycometabolism and memory function in type 2 diabetic rats is improved by moderate exercise, possibly via enhanced lactate transport to neurons by MCT2.
A type of bacterium usually found in the human mouth, Fusobacterium nucleatum (F. nucleatum), has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan. The bacteria are a causative agent of periodontal disease and though it can be found among the intestinal flora, it hasn't been the focus of much research until now.
We all know that running causes a bit of inflammation and soreness, and that's just the price you pay for cardiovascular health. You know; no pain, no gain. Well, maybe not. New research from BYU exercise science professors finds that pro-inflammatory molecules actually go down in the knee joint after running.
Loss of a key protein has been discovered as the event that leads to defects in skeletal development, including reduced bone density and a shortening of the fingers and toes -- a new potential target for the diagnosis and treatment of bone diseases such as osteoporosis.
Scientists have focused on certain p53 mutations that generate mutant proteins that promote cancer growth and metastasis. The variants studied are truncated -- they lack half of the domains, or units, of the full-length p53 protein, which enable full-length p53 to enter the cell nucleus and bind DNA, essential in its normal tumor-suppressor function. The truncated mutants act by perturbing mitochondrial function, the team proposes.
Researchers at UMass Medical School and the University of Toronto have discovered the first known 'off-switches' for CRISPR/Cas9 genome editing, providing much greater control over the edits, according to a new study published in Cell. Erik Sontheimer, PhD, led the research at UMMS.
A researcher from UH Seidman Cancer Center will discuss his upcoming immunotherapy clinical trial for triple-negative breast cancer at 2016 San Antonio Breast Cancer Symposium. Joseph Baar, MD, PhD, Director of Breast Cancer Research at UH Seidman Cancer Center, will share details about a phase II clinical trial testing the effectiveness of combining carboplatin and nab-paclitaxel with an immunotherapeutic agent called pembrolizumab in patients with metastatic triple-negative breast cancer.