In a study appearing in the Sept. 13 issue of JAMA, Jouke T. Annema, M.D., Ph.D., of the Academic Medical Center, Amsterdam, and colleagues examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung cancer.
The Second Panel on Cost-Effectiveness in Health and Medicine reviewed the current status of the field of cost-effectiveness analysis and developed a new set of recommendations, with major changes including the recommendation to perform analyses from 2 reference case perspectives and to provide an impact inventory to clarify included consequences, according to an article appearing in the Sept. 13 issue of JAMA.
Implementing an analytic tool that allocates clinical care costs and quality measures to individual patient encounters was associated with significant improvements in value of care for 3 designated outcomes -- total joint replacement, laboratory testing among medical inpatients, and sepsis management, according to a study appearing in the Sept. 13 issue of JAMA.
Smokers without obvious signs of heart disease were more likely than nonsmokers and former smokers to have thickened heart walls and reduced heart pumping ability. The longer and more cigarettes people smoked, the greater the damage to their hearts' structure and function. Heart measures in former smokers were similar to nonsmokers, suggesting that quitting may reverse tobacco-related damage.
New research from The Wistar Institute demonstrates how a drug already in clinical trials could be used to boost anti-tumor immunity and cause T-cells to target the cancer directly while minimizing side effects.
How the brain responds to nicotine depends on a smoker's belief about the nicotine content in a cigarette, according to new research from the Center for BrainHealth at The University of Texas at Dallas. The study, recently published in Frontiers in Psychiatry, found that smoking a nicotine cigarette but believing that it lacked nicotine failed to satisfy cravings related to nicotine addiction.
Scientists at Baylor College of Medicine, the National Institutes of Health and Virginia Tech Carilion Research Institute have discovered a new mechanism in the mouse brain that regulates obesity. The study, which appears in Cell Reports today, shows that this new mechanism can potentially be targeted to treat obesity.
Graded aerobic treadmill testing is safe, tolerable, and useful in evaluating and managing cases of sports-related concussion in children and adolescents. This is the finding of a new study reported in the Journal of Neurosurgery: Pediatrics.
Researchers from Massachusetts Eye and Ear have, for the first time, linked symptoms of difficulty understanding speech in noisy environments with evidence of cochlear synaptopathy, a condition known as 'hidden hearing loss,' in college-age human subjects with normal hearing sensitivity.
Freestanding children's hospitals had the largest financial losses for pediatric inpatients covered by Medicaid, suggesting hospitals may be unlikely to offset decreased Disproportionate Share Hospital payments from caring for fewer uninsured patients as a result of health insurance expansion, according to an article published online by JAMA Pediatrics.