Newly released findings from national HIV surveys in Zimbabwe, Malawi, and Zambia reveal extraordinary progress in confronting the HIV epidemic. These three countries in Southern Africa have been heavily affected by HIV, and now there are encouraging signs that the epidemics are going in the right direction.
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), together with collaborators in Europe, discovered that a common type of cell within the human reproductive and intestinal tracts assists HIV in infecting immune cells. Understanding how these cells aid HIV could lead to new methods that prevent HIV transmission.
Scientists at the National Institutes of Health have found that the presence of the protein alpha-4 beta-7 integrin on the surface of HIV and its monkey equivalent -- simian immunodeficiency virus, or SIV -- may help explain why an antibody protected monkeys from SIV in previous experiments.
A team from the Spanish National Research Council (CSIC) has developed a biosensor that can detect type 1 HIV during the first week after infection. The experiments, performed on human serum, detect the p24 antigen, a protein present in the HIV-1 virus. This new technology, which has been patented by CSIC, detects the protein at concentrations 100,000 times lower than in current techniques.
Delivering on the promise of preventing HIV infections with antiretroviral medicines, or pre-exposure prophylaxis (PrEP), requires thinking about PrEP as a nine-step continuum of preventive care, Brown researchers write in the journal AIDS.
Potent HIV-specific CD8+ T cells that are able to kill HIV-producing cells and reduce the seeding of the HIV reservoir are only detected at peak viremia in acute HIV infection.
In the transmission of HIV-1 from mother to child only a subset of a mother's viruses infects their infants either in utero or via breastfeeding, and the viruses that are transmitted depend on whether transmission occurs during pregnancy or through breastfeeding
Delinquent youth are more likely to have high-risk HIV/AIDS sexual behaviors as they age, including multiple sexual partners and unprotected vaginal sex with a high-risk partner, reports a Northwestern Medicine study. The study tracked the youth 14 years after detention.
Landmark study proves that 'super-boosting' approach counters negative interaction between key HIV and TB drugs The non-profit research and development organization Drugs for Neglected Diseases initiative (DNDi) has released results of a study in South Africa that will make it easier for healthcare workers to treat children living with HIV who are co-infected with tuberculosis (TB).
A special issue on progress toward a cure for HIV includes a description of a previously unreported study started in the early 2000s that describes AIDS patients currently ages 51-67 in good health.