Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen provide better pain control and have fewer adverse effects than codeine, a commonly prescribed opioid, when prescribed after outpatient surgery, according to new research published in CMAJ (Canadian Medical Association Journal).
Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths--nearly 50,000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical models, an understanding of the biological alterations that occur in the brains of people who chronically use opioids and who are diagnosed with OUD remains limited.
Lab animals deficient in vitamin D crave and become dependent on opioids, which is curbed when normal levels of the vitamin are restored. Human health records indicate that people with low vitamin D are more likely to use and misuse opioids. Study results suggest a potential role for vitamin D supplementation in fighting opioid addiction.
Surgeons can ease their patients' pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.
Researchers at UC San Diego, San Diego State University, and international collaborators have designed and validated a prediction model to signal counties at risk of future overdose death outbreaks.
New research published online in the journal Substance Use & Misuse is good news for those struggling with alcohol dependence: the possibility of ending this dependency gets easier with age. Moreover, more than half of individuals who have been dependent on alcohol are free of any addictions or mental illness, and nearly 40% are in excellent mental health.
Underage youth consumed $17.5 billion worth, or 8.6 percent, of the alcoholic drinks sold in 2016. Products from three alcohol companies - AB Inbev, MillerCoors and Diageo - accounted for nearly half of youth consumption, according to a new study from researchers at the University of North Carolina at Chapel Hill, Johns Hopkins and Boston University.
People who have a high sensation-seeking personality trait may be more likely to develop an addiction to cocaine, according to a Rutgers study.
As many older adults get back to normal life across the United States thanks to high rates of vaccination and lower COVID-19 activity, a new poll suggests many should watch their alcohol intake.