Researchers at UC San Diego Moores Cancer Center, with colleagues from Memorial Sloan Kettering Cancer Center and Fox Chase Cancer Center, have determined that a specific region of the small bowel, called the duodenal-jejunal flexure or DJF, shows a high frequency of gastrointestinal stromal tumors (GISTs) with mutations of the NF1 gene.
The field of immunotherapy is moving forward at an unprecedented rate and cancer immunotherapy, in particular, has recently come of age!
By combining an FDA-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, Duke researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease.
A drug-like molecule developed by Duke Health researchers appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn's disease.
Immortalization of cells is a necessary step in the development of cancer, and scientists think that the main cause is turning on an enzyme -- telomerase -- that lengthens chromosomal telomeres and prevents normal cell death. A new study by UC Berkeley scientists shows that turning on telomerase is not a one-step process. In melanoma, and probably other cancers, a mutation turns up telomerase slightly, keeping the cell alive long enough for other changes that up-regulate telomerase.
A study led by Wistar scientists describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer-specific protein.
A recent paper published in Age & Ageing, the scientific journal of the British Geriatrics Society, finds that current smoking in older people increases the risk of developing frailty, though former smokers did not appear to be at higher risk.
When astronauts travel in space they can't see or even feel radiation. However, NASA's Human Research Program (HRP) is studying the effects radiation plays on the human body and developing ways to monitor and protect against this silent hazard.
Vitamin C may 'tell' faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers.
Women who live in areas with higher levels of outdoor light at night may be at higher risk for breast cancer than those living in areas with lower levels, according to a large long-term study from Harvard T.H. Chan School of Public Health. The link was stronger among women who worked night shifts.