Results of a randomized controlled trial suggest that systematic bright light exposure can improve sleep for fatigued people who have been treated for cancer.
Cleveland Clinic researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate cancer. The research, led by Nima Sharifi, M.D., Cleveland Clinic Lerner Research Institute, Department of Cancer Biology, shows that men who lack a certain subtype of the gene may be more susceptible to aggressive prostate cancer that does not respond to treatment.
A research team at the Duke Cancer Institute has found a new way to keep the immune system engaged, and is planning to test the approach in a phase 1 clinical trial.
A new study adds to accumulating research that gum disease is associated with some cancer risk. It reports a 24 percent increase in the risk of cancer among participants with severe gum disease. The highest risk was observed in cases of lung cancer, followed by colorectal cancer.
Researchers at Insilico Medicine, AgeX Therapeutics and the Biogerontology Research Foundation have published a landmark study titled 'Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells' in the journal Oncotarget.
Obese women are 12 times more like to get cancer than those of a normal weight. Obese men are twice as likely to develop this disease. The data is the result of the largest Spanish study ever in this field, involving a 10-year follow up of 54,000 people from seven autonomic communities. Only 26 percent of those taking part had a normal weight. The rest were either obese or overweight.
Researchers of the Sarcoma group of the Oncobell program -- Bellvitge Biomedical Research Institute (IDIBELL) have successfully tested a new combined therapy for the treatment of this rare, aggressive tumor type, which affects children and adults.
The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer.
Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Now, a research team from Perelman School of Medicine at the University of Pennsylvania says it may have determined the reason for the melanoma-protective effect.
Published in Nature Cell Biology (NCB), the study shows that the EXD2 protein is critical for the mitochondria, the cell's powerhouses, to produce energy. This protein was previously thought to be located in the cell nucleus and to be involved in DNA repair. The results contribute to our basic understanding of mitochondria and suggest that EXD2 could be important for fertility and represent a potential target for cancer therapy.