In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.
A collaborative research team has uncovered new information that more accurately explains how cancerous tumors grow within the body. This study is currently available in Nature Genetics.
USC researchers have pinpointed a remedy to thwart a protein that helps the metastatic spread of breast cancer, a leading cause of death for women. The findings appear today in Nature Communications.
Although the genitourinary syndrome of menopause (GSM) is more prevalent in survivors of breast cancer than in other menopausal women, it is commonly undiagnosed and untreated. This led NAMS and ISSWSH to form a multidisciplinary Consensus Panel to develop recommendations for clinicians to manage GSM in women with or at high risk for breast cancer. The recommendations are published online in NAMS' official journal, Menopause.
A unique tissue type in many ways, the mammary gland is cloaked in mysteries that scientists puzzle over. In a paper in Science, the University of Pennsylvania's Rumela Chakrabarti and colleagues describe a newly identified connection between mammary stem cells and macrophages, a type of immune cell. The crosstalk between these two cell types is crucial for mammary gland development, and may also figure into the biology of breast cancer.
Researchers have made new discoveries about how an immune cell known as the macrophage, which normally fights infection by swallowing foreign invaders, nurtures mammary gland stem cells through a chemical signaling molecule. The study may provide important clues about the roles of macrophages in breast cancer progression.
A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options.
For women, mammograms are a sometimes uncomfortable, but necessary, annual ritual. But this procedure doesn't always provide accurate results, and it exposes women to X-rays. In a study appearing in ACS' journal Molecular Pharmaceutics, scientists report that they have developed a non-invasive 'disease screening pill' that can make cancerous tumors light up when exposed to near-infrared light in mice without using radiation.
Scientists have developed a new compound that inhibits the spread of cancer cells, which is what makes the disease so lethal. The compound, metarrestin, significantly reduced metastasis by human prostate, pancreatic and breast cancer transplanted into mice. Mice treated with it had fewer metastatic tumors and lived longer than mice that did not receive treatment. Metarrestin is being submitted to the FDA as an investigational drug.
The team of researchers at Kaunas University of Technology, Lithuania are developing mathematical methods which could help diagnose breast cancer. Applying deep learning method, the researchers are aiming to 'teach' computers to recognize malignant lesions, which would allow at least partially automatize and enhance the accuracy of diagnosing breast cancer.