Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technische Universität München (TUM), and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.
Rare variants combined with background genetic risk factors may account for many unexplained cases of familial breast cancer, and knowing the specific genes involved could inform choice of prevention and treatment strategies, according to findings presented in a plenary session at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla.
A sharp rise in the number of women seeking BRCA genetic testing to evaluate their risk of developing breast cancer was driven by multiple factors, including celebrity endorsement, according to researchers at the University of Georgia.
This new knowledge may be key to the early detection of patients who would benefit from zoledronic acid and those who should be spared, and it may accelerate the administration of the first preventive treatment of metastasis.
Breast cancer cells recycle ammonia, a waste byproduct of cell metabolism, and use it as a source of nitrogen to fuel tumor growth, report scientists from Harvard Medical School. The insights shed light on the biological role of ammonia in cancer and may inform the design of new therapeutic strategies to slow tumor growth.
Breast cancer is the second most commonly diagnosed cancer in women. Fortunately, the rate at which we're learning about this disease means patients have a lot more treatment options and far better chances of survival than they did 100 years ago. In observance of Breast Cancer Awareness Month, Reactions describes what's changed about how we treat breast cancer and what patients can expect in the future: https://youtu.be/QcgnVuRx20s.
A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study. Researchers said the technology has the potential to reduce unnecessary surgeries.
Differences in insurance account for a substantial proportion of the excess risk of death from breast cancer faced by black women, according to a new study.
High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so that they facilitate the cancer's spread instead of stopping it.
A new study published in the Journal of the National Cancer Institute finds that cryotherapy, specifically having chemotherapy patients wear frozen gloves and socks for 90-minute periods, is useful for preventing symptoms of neuropathy.