Scientists at the University of Bath funded by Cancer Research UK have custom-built a molecule which stops breast cancer cells from multiplying in laboratory trials, and hope it will eventually lead to a treatment for the disease.
A new article published by JAMA Oncology compares outcomes for combined mammography and MRI or ultrasonography screenings for new breast cancers in women who have previously undergone breast conservation surgery and radiotherapy for breast cancer initially diagnosed at 50 or younger.
Your doctor is an expert with many years of experience. So when she tells you, upon reviewing all the fancy tomographic imaging you had done, that the tenderness in your breast is just some minor irritation, you want to believe her and leave it at that.
Anticancer agents targeting microtubule from marine sources hold great potential in the field of cancer therapeutics and are gradually advancing in the clinical setup.
A position statement on the use of hormone therapy for menopausal and postmenopausal women from The North American Menopause Society (NAMS) has been published online in Menopause. 'The goal of the Society's position statement is to provide excellent, evidence-based, current clinical recommendations to menopause practitioners for the improvement of care for women depending on them to help relieve menopause symptoms,' says Dr. JoAnn Pinkerton, NAMS executive director.
Researchers conducted an analysis that included nearly 10,000 women with the BRCA1 or BRCA2 genetic mutations to estimate the age-specific risk of breast or ovarian cancer for women with these mutations, according to a study published by JAMA.
A large scale study of women carrying faults in important cancer genes should enable doctors to provide better advice and counselling for treatments and lifestyle changes aimed at reducing this risk.
Estrogens act as a driving force of both healthy and cancerous mammary cell growth by binding to receptors that include GPER, which is generally located in cell membranes. Studies have revealed the unusual presence of this receptor in the nuclei of fibroblasts surrounding mammary tumor cells. Researchers at UNIGE have discovered that this is in fact another version of GPER with different properties. The fibroblasts carrying this variant promote the migration of neighboring malignant cells.
Cell-killing chemotherapies are designed to shrink cancerous tumors by accumulating in their ill-formed blood and lymph vessels, delivering a toxic dose to the cancer cells. A team of researchers at the Wyss Institute has developed a new drug delivery platform that uses safe, low-energy ultrasound waves to trigger aggregates of chemotherapy-containing nanoparticles to break apart precisely at tumor sites, resulting in dramatically improved targeting efficacy and toxicity profile in mouse models of breast cancer.
Simultaneous injections of the radiopharmaceuticals fluorine-18 fluorodeoxyglucose (18F-FDG) and 18F-sodium fluoride (18F-NaF) followed by quantitative scanning significantly improves image quality and detection of bone metastases at a lower dose, according to research presented at the 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).