Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers. This finding, published in Cell, helps explain how some non-smoking-related lung cancers develop.
For all cancer sites combined, cancer death rates continued to decline in men, women, and children in the United States from 1999 to 2016. Overall cancer incidence rates, or rates of new cancers, decreased in men from 2008 to 2015, after increasing from 1999 to 2008, and were stable in women from 1999 to 2015. In a special section of the report, researchers looked at cancer rates and trends in adults ages 20 to 49.
Intensive radiotherapy can be toxic in 60% of patients with tumors located in the gastrointestinal cavity. Increases in URI levels protect mice against high-dose ionizing radiation-induced gastrointestinal syndrome and enhance mouse intestinal regeneration and survival in 100% of the cases. This finding could be useful to mitigate side effects of other sources of intensive radiation, such as nuclear accidents, nuclear warfare or the exposure to cosmic radiation during space explorations.
Early-onset colorectal cancer -- cancer occurring before age 50 -- is rising most rapidly in Western states, where healthy behaviors are prominent, according to a new study.
Researchers in the UK have developed a new method for evaluating plutonium workers' historical internal radiation exposure in a study funded by the National Institute for Health Research. They focused their efforts on workers employed at the start of plutonium operations at the Sellafield (formerly Windscale) nuclear reprocessing facility in the UK.
A University of California, Riverside, research team has come up with a new approach to targeting cancer cells that circumvents a challenge faced by currently available cancer drugs.
First causal evidence that oxidative stress works directly on telomeres to speed cellular aging.
Brain tumours are the leading cause of non-accidental death in children in Canada, but little is known about when these tumours form or how they develop. Researchers have recently identified the cells that are thought to give rise to certain brain tumours in children and discovered that these cells first appear in the embryonic stage of a mammal's development - far earlier than they had expected.
A large study of postmenopausal women indicated that quitting cigarette smoking was associated with significantly reduced risk of bladder cancer. The most significant reduction in risk occurred in the first 10 years after quitting, with a modest but continued decline in later years.
Fluorinated firefighting foam is a leading cause of PFAS water contamination and is associated with cancer and endocrine disruption. A panel of independent fire-safety experts from across sectors demonstrate that PFAS chemicals are similarly toxic to PFOA and PFOS and are harder to control, leading to increased pollution, exposure, and presence in the food chain. A new report demonstrates the efficacy and viability of fluorine-free foams and calls for a global PFAS ban with no exemptions.