University of California San Diego School of Medicine researchers found that treating patients with personalized precision medicine that combined therapies to target multiple alterations improved outcomes in patients with therapy-resistant cancers.
Scientists from Far Eastern Federal University (FEFU) in cooperation with colleagues from Blokhin Russian Cancer Research Center (Moscow), Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors. Researchers revealed a number of proteins, which are potential targets to attack during complex antitumor therapy. A related article was published in Oncology Reports.
Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analyzing the genetic faults in a sample of their blood, according to research published in Nature Medicine today (Monday).
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. These very sick patients are often unable to receive the only cure -- a bone marrow transplant. Now, an international team of scientists report in Nature Cell Biology on a long-overlooked part of a leukemic cell's internal machinery, where they may have found a key to treating the aggressive blood cancer.
An advance in the cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings.
Study finds drug could have new applications in non-diabetics.
A protein called p53 suppresses and kills cancer in people. However, a defective, mutant form of p53 helps cancer cells grow and multiply. Researchers at the University of Missouri have now found that a combination drug therapy reduces the spread of triple negative breast cancer to other locations of the body by 50 percent.
NRG Oncology, a National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group conducting practice-changing clinical and translational research, has been awarded funding of over $95 million by the NCI for the next six years to continue its work as a lead protocol organization (LPO) program.
In a new study published today in the Journal of Periodontology researchers found that using psychological techniques to communicate the risk of developing periodontal disease to patients improved dental hygiene over a three month period.
Researchers from King's College London, Harvard and INSERM-Paris have discovered a new way to measure brain function in milliseconds using magnetic resonance elastography (MRE). This could help with diagnosing and understanding neurological diseases like Alzheimer's, dementia, multiple sclerosis, or epilepsy.