Thirty-six percent of Hispanic families in the U.S. with a common form of retinitis pigmentosa got the disease because they carry a mutation of the arrestin-1 gene, according to a new study from researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.
Activity monitors or fitness trackers are fun and informative gadgets to help track daily physical activity. But as a source of objective data for research on the health benefits of exercise, they're not yet fully up to speed, reports a paper in Progress in Preventive Medicine, the official journal of the European Society of Preventive Medicine. The journal is published by Wolters Kluwer.
Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness -- a variance that long has puzzled researchers. Now a study has found that the gene mutation's toxic effects require higher than normal levels of a protein called suPAR to trigger the onset and progression of the disease.
Going for a walk outside, reading, listening to music--these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer's disease, suggests a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
The immunotherapy nivolumab is kinder than chemotherapy for people with advanced head and neck cancer -- easing many of the negative effects of the disease on patients' quality of life.
Some insulin is still produced in almost half of the patients that have had type 1 diabetes for more than ten years. Patients with remaining insulin production had much higher levels in blood of interleukin-35, They also had much more immune cells that produce interleukin-35 and dampen immune attacks.
Cleveland Clinic researchers have shown for the first time how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they are metabolized. Their pre-clinical findings, just published in Cell Chemical Biology, may lay the foundation for improving therapies for treatment-resistant, aggressive prostate cancer.
Around one in five children with Tourette syndrome, a neurological disorder characterized by involuntary movements and vocalizations, met criteria for autism in a study headed by UC San Francisco. But this prevalence may be more a reflection of similarity in symptoms than actual autism, according to the study's researchers.
Parkinson's disease is commonly thought of as a movement disorder, but after years of living with the disease, approximately 25 percent of patients also experience deficits in cognition that impair function. A newly developed research tool may help predict a patient's risk for developing dementia and could enable clinical trials aimed at finding treatments to prevent the cognitive effects of the disease.
A new study found that applying continuous positive airway pressure (CPAP), a form of non-invasive ventilation, decreased mortality in children with respiratory distress. Findings from the trial in Ghana indicated that the procedure especially benefited children less than one year of age, confirmed that no serious adverse events were associated with the treatment, and is a step forward in treating children with respiratory distress in resource-limited settings.