In one of the largest studies to measure the burden of antibiotic resistance in a low- or middle-income country, researchers at the Center for Disease Dynamics, Economics & Policy report that in-hospital mortality is significantly higher among patients infected with multi-drug resistant (MDR) or extensively drug resistant (XDR) pathogens including Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii.
For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalised treatment in the future.
A patient's weight history could help identify those at increased risk of dying. Using data for nearly 6,200 people from the Framingham Heart Study, this study incorporated weight history to examine the association between obesity and risk of death because many studies typically rely on weight status at a single point in time.
Newcastle University experts are chairing a national session on new guidelines for the early detection and treatment of sarcopenia -- a loss of muscle strength that affects many older people in the UK.
A new pharmacological agent demonstrates promising results for the prevention of a wide range of heart rhythm disorders, including both cardiac and brain injury-induced arrhythmia and the most common and malignant among them: atrial fibrillation. Furthermore, the compound demonstrates significant activity in conditions of reduced blood flow to the heart caused by obstructed arteries. The study is published in the open-access journal Research Results in Pharmacology.
Children born prematurely often experience serious problems with the gastrointestinal tract and therefore have increased risk of developing life-threatening bowel infection. Now researchers from the University of Copenhagen have shown, in a study on pigs, that transplantation of faeces from healthy pigs changes the bowel's bacterial composition in those born prematurely and protects them from the fatal bowel disease necrotizing enterocolitis (NEC).
Investigating a new marker for chronic inflammation GlycA, researchers have found that chronic inflammation is linked to increased risk for shorter lifespan and several organ-related diseases. The findings were made through investigating GlycA measurements with Nightingale Health's blood testing technology. The results highlight a potential use for measuring GlycA in healthcare.
Outbreaks of norovirus in health care settings and outbreaks caused by a particular genotype of the virus are more likely to make people seriously ill, according to a new study in The Journal of Infectious Diseases. Based on an analysis of nearly 3,800 US outbreaks from 2009 to 2016, the research confirms several factors that can make norovirus outbreaks more severe and may help guide efforts to develop a vaccine to prevent this highly contagious disease.
Age-related declines in abstract reasoning ability predict increasing depressive symptoms in subsequent years, according to data from a longitudinal study of older adults in Scotland. The research is published in Psychological Science, a journal of the Association for Psychological Science.
'Pancreatic Cancer Across Europe,' published by United European Gastroenterology (UEG) to coincide with World Pancreatic Cancer Day, examines the past and current state of pancreatic cancer care and treatment, as well as the future prospects, such as targeting the microbiome, for improving the prognosis for patients. Whilst lung, breast and colorectal cancer have seen significant reductions in death rates since 1990, deaths from pancreatic cancer continue to rise.