Researchers have identified a therapeutic target to prevent or delay heart failure from pressure overload of the heart, and a potential biomarker for the same. They say their animal studies carry clinical and translational potential. Mouse-model experiments showed that preventing the early infiltration of CCR2+ macrophages into the heart, after experimental pressure overload, significantly lessened the heart's enlargement and reduced pumping ability that leads to later heart failure.
Every year, approximately 12 million adults in the US are diagnosed with Chronic Obstructive Pulmonary Disease, and 120,000 die from it. For people with COPD, Haemophilus influenzae, a bacterium, can be particularly dangerous. Now, researchers have unraveled how the bacterium adapts quickly, which may open new avenues for therapy for COPD and other diseases such as ear infections or pneumonia.
People who are living with HIV in Ontario have access to good health care and medications, yet they are still dying younger and at substantially higher rates than the rest of the population, according to a new study published today.
The decline in cancer of the intestines -- colorectal cancer -- is one of the major success stories of the past 30 years in Europe say researchers, as they predict that in 2018 death rates from the disease will continue to fall by around 7 percent compared to 2012. In a study published in the leading cancer journal Annals of Oncology, researchers predict that death rates in the European Union for most cancers will continue to fall this year, compared to 2012.
About five percent of older adults on Medicare don't have a 'personal physician,' and this group scores lower on measures of healthcare quality, reports a study in the April issue of Medical Care, published by Wolters Kluwer.
A recent study in 2500 participants in the Offspring cohort of the Framingham Heart Study looked at the value of measuring blood levels of EPA and DHA omega-3 fatty acids to assess an individual's risk for developing certain diseases and determined that the risk for death from any cause was reduced by about 33% in participants with the highest omega-3 blood levels.
Adults who have undergone successful cancer treatment years or decades previously become fatigued more quickly than their peers who don't have cancer histories, according to a new study in the journal Cancer from scientists at Johns Hopkins Bloomberg School of Public Health.
Researchers at Vanderbilt University Medical Center have found a way to search genetic data in electronic health records to identify undiagnosed genetic diseases in large populations so treatments can be tailored to the actual cause of the illness.
Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a study published the March 14, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study measured the women's cardiovascular fitness based on an exercise test.
Roughly one in four elderly Japanese women will live below the poverty level in the near future, predicts a model of the Japanese pension system. Never-married and divorced women will be the most affected, with around 50 percent of these women predicted to become impoverished in the next 50 years.