Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex (TSC), doctors at The University of Texas Health Science Center at Houston (UTHealth) reported that a skin cream containing rapamycin significantly reduced the disfiguring facial tumors affecting more than 90 percent of people with the condition.
Researchers at the University of Lille developed a matrix-assisted ion source for mass spectrometry that can liberate lipids and metabolites from the skin without causing pain. Now, they have optimized protein measurement using this device. The device can be used to differentiated normal from cancerous tissues.
Facial angiofibromas are disfiguring growths and these lesions occur in most people with tuberous sclerosis complex, a genetic disorder where growths can appear throughout the body. Current treatments for these facial growths include laser surgery, cryotherapy, dermabrasion and other similar procedures that can be painful and cause scarring but can't prevent recurrence of the lesions.The results of a clinical trial of 179 patients showed improvement in the appearance of these lesions with the use of topical rapamycin.
Adults with severe eczema could face an increased risk of experiencing non-fatal cardiovascular disease, according to the largest ever study to examine the link, published in the BMJ.
An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation -- a key marker of future risk of major cardiovascular events -- unlike other antibodies that target different aspects of the immune system.
This vision of simplifying disease diagnosis using topically applied nanotechnology could change the way skin diseases such as abnormal scars are diagnosed and managed.
Even if the wound looks superficially harmless, steam burns must be cooled persistently. Empa researchers have now been able to show for the first time how hot steam achieves its vicious effect: it penetrates the upper skin layer and can cause severe burns in the lower skin layers -- initially almost invisible.
A tool to accurately determine which early-stage patients are at risk of dying from mycosis fungoides and which patients are likely to only require conventional therapy is desperately needed. Investigators from Brigham and Women's Hospital have found that next-generation, high-throughput sequencing of a specific gene (T-cell receptor beta or TCRB) is a stronger predictor of which early-stage patients will develop aggressive, progressive MF than any other established factor.
An analysis estimates using teledermoscopy (dermatologic care that uses information and communications technology and digital dermoscopic images) in Australia for skin cancer referrals would cost extra per case but could achieve clinical resolution faster.
A new drug could ease the distress of men and women who suffer from baldness, according to researchers from the University of Manchester's Centre for Dermatology Research. The study from the laboratory of Professor Ralf Paus, is published today in the open-access journal PLOS Biology.