Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research (MPI-P) have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors.
Exploring whether hand-holding or squeezing a stress ball would reduce patient anxiety during skin cancer surgery under local anesthesia was the main focus of this randomized clinical trial. The study of 135 patients at an urban academic medical center reports that patients who used stress balls or whose hands were held weren't less anxious, didn't experience less pain and were no more satisfied with the procedure than other patients.
Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay -- sometimes even after treatment has concluded.
Gyms are places people go to get healthier. But nearly half the gyms in the U.S. contain a potentially addictive carcinogen -- tanning beds, report UConn researchers in the July 18 issue of JAMA Dermatology. Exercise reduces the risk of every cancer except melanoma. Tanning beds in gyms make tanning seem like part of a healthy lifestyle, undermine public health messaging and target a vulnerable population.
A new study published in Annals of Allergy, Asthma and Immunology shows that eczema symptoms can have a profoundly negative impact on quality of life for those who suffer -- even worse than for those with common chronic illnesses like heart disease, diabetes and high blood pressure.
Adam Friedman, M.D., professor of dermatology at the GW School of Medicine and Health Sciences, and his team investigated the use of nanotechnology to improve efinaconazole treatment and make it more cost effective.
New research shows that death and recurrence are rare in children with Stevens-Johnson syndrome and toxic epidermal necrolysis, but children who experience these skin conditions have high rates of complications that treatment strategies varied among health care providers.
UC San Francisco researchers have identified the sequence of genetic changes that transform benign moles into malignant melanoma in a large cohort of human skin cancer patients and have used CRISPR gene editing to recreate the steps of melanoma evolution one by one in normal human skin cells in the lab. The research identified key molecular warning signs that could be used by clinicians to catch developing cancers before they spread and could also lead to new targeted therapies.
Topical retinoids, which target retinoic acid receptors, are commonly used to treat acne. New research published in the British Journal of Dermatology reveals that trifarotene, a fourth-generation retinoid with potent and selective activity against only one particular retinoic acid receptor, may have an improved efficacy and safety profile compared with less selective retinoids.
Both dogs and humans can suffer from ichthyosis, a disorder in which the skin becomes very dry, scaly, and prone to secondary infections. A team led by Penn's Elizabeth Mauldin uncovered new details about one form of the disease and took a step toward developing a topical therapy.