Scientists have found that stem cells in the skin remember an injury, helping them close recurring wounds faster. The discovery could advance research and treatment of psoriasis and other inflammatory diseases.
Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural 'brakes' in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes. The study, which involved colleagues from Hamburg and Würzburg, could pave the way for more effective cancer therapies. It is being published in the journal Cell Reports.
A new Cleveland Clinic study underscores the importance of early detection and treatment of melanoma, the deadliest form of skin cancer. The research, published online today in the Journal of the American Academy of Dermatology, indicates that the sooner patients were treated, the better their survival, particularly for stage I melanoma.
In the first study of its kind, an international team of genomics researchers have identified new regions of the genome that are associated with skin color variation in some African populations. These newly identified regions include genes that repair DNA damage caused by UV light, are associated with albinism and contribute to the production of a novel lysosomal protein. Lysosomes are sub-cellular structures that play roles in optimizing nutrition and fighting infections and now, with these findings, in pigmentation.
A study of diverse African groups led by University of Pennsylvania geneticists has identified new genetic variants associated with skin pigmentation. The findings help explain the vast range of skin color on the African continent, shed light on human evolution and inform an understanding of the genetic risk factors for conditions such as skin cancer.
A protein known to play a significant role in the development of psoriasis can be prevented from functioning without posing a risk to patients, scientists at King's College London have found. The study confirmed that a group of inflammatory proteins called 'IL-36' play a significant role in the development of psoriasis and can, in theory, be blocked without posing a risk to patients.
A new research letter published by JAMA Dermatology analyzes People magazine's World's Most Beautiful list to compare standards of beauty in 1990 with the present day.
Timely treatment for cancer is important and a new article published by JAMA Dermatology examines how delays of surgery for melanoma vary by insurance type.
A neurotransmitter study in mice found that BNP is involved in relaying itching sensations but not pain. A better understanding of pain and itch pathways could help researchers develop targeted therapies for diseases with chronic itching, including multiple sclerosis and kidney failure.
By carefully tracing a line of at least 2 millimeters outside of and around the edges of a mole that is suspected of being a cancer, doctors can remove all of its cells and avert the need for a second surgery.