A new article published by JAMA Dermatology uses a nationwide database of emergency department (ED) visits to examine herpes zoster (HZ, shingles)-related ED utilization and costs.
The use of topical antibiotics can dramatically alter communities of bacteria that live on the skin, while the use of antiseptics has a much smaller, less durable impact. The study, conducted in mice in the laboratory of Elizabeth Grice, PhD, an assistant professor of Dermatology in the Perelman School of Medicine at the University of Pennsylvania, is the first to show the long-term effects of antimicrobial drugs on the skin microbiome.
Despite mixed evidence recently about an association between atopic dermatitis and cardiovascular disease, a new study that analyzed more than 250,000 medical records suggests there is no link.
The results of a study presented today at the Annual European Congress of Rheumatology 2017 have shown that the combined use of two measurements to accurately predict the risk of relapse in patients with rheumatoid arthritis (RA) allows successful dose reduction (tapering) of their disease modifying anti-rheumatic drugs (DMARDs). This in turn increases the cost-effectiveness of each DMARD treatment.
The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference revealed promising data supporting two new drug classes for the treatment of psoriatic arthritis (PsA).
Nagoya University research identified a patient with the whole-body skin disease epidermolytic ichthyosis that had been inherited as a germline mutation from her father with the milder epidermolytic nevus. Analysis of genomic DNA from the patient revealed a mutation in the keratin 10 gene, which was identical to that observed in cells taken from patches of thickened skin on the father's body. Assessing transmission risk of such diseases allows affected couples to receive genetic counseling.
Despite legislation prohibiting the use of ultraviolet (UV) indoor tanning facilities by minors, one in every five tanning salons in US states where such bans are in place stated over the phone that they would allow an underaged caller to do so. Many others provide inaccurate health information about indoor tanning, says Leah Ferrucci, of the Yale School of Public Health in the US. She led a study in Springer's journal Translational Behavioral Medicine.
Investigators at Massachusetts General Hospital and Dana-Farber Cancer Institute have developed a way of increasing pigmentation in human skin without the damaging effects of ultraviolet radiation.
Researchers in Boston have developed a class of small molecules that successfully penetrates and darkens human skin samples in the laboratory. The drug also generates protective tans in red-haired mice, which are more susceptible to skin cancer via ultraviolet (UV) radiation. The molecule works by stimulating cells to produce more UV-absorbing pigments, but more preclinical tests need to be done before it is proven safe in humans. The study appears in the journal Cell Reports.
Penn researchers studying an inherited disorder of skin, hair follicles, nails, sweat glands, and teeth called hypohidrotic ectodermal dysplasia (HED) have identified a mechanism that may also be disrupted in male pattern baldness, a more common condition.