Severe burns can leave physical and psychological scars, especially in children. When a burn patient enters the clinic, doctors use factors such as the depth and size of the burn, as well as the time required for skin healing--or re-epithelialization--to determine the best course of treatment. Now, researchers reporting in ACS' Journal of Proteome Research have found another, possibly more accurate way to classify burn severity: analyzing proteins in blister fluid.
This study looked at trends over time in oral antibiotic prescribing by dermatologists using commercial insurance claims data for almost 986,000 courses of oral antibiotics prescribed by nearly 12,000 dermatologists.
A team of investigators from the University of Colorado College of Nursing at CU Anschutz Medical Campus and National Jewish Health has identified comprehensive guidelines for managing severe atopic dermatitis (AD), the most common form of eczema.
Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing physicians in a region and higher population of Caucasians.
The specialty of dermatology is one of the least diverse medical fields. In this study, a survey was conducted among 155 medical students (58 percent of whom were nonwhite) to understand perceived barriers to pursuing a career in dermatology by minority medical students.
The identification of the recent spread of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in a Brooklyn religious enclave is helping medical experts better understand how certain high-risk populations can drive the evolution of antimicrobial resistance and identify steps that can be taken to curtail its spread, according to a new study.
Some dermal fibroblasts can convert into fat cells that reside under the dermis, giving skin a youthful look and producing peptides that fight infections. University of California San Diego School of Medicine researchers and colleagues show how this happens and what causes it to stop as people age.
An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a chronic disease that can affect multiple organs, with a drug approved for rheumatoid arthritis. Successful treatment of two other patients with similarly severe disease suggests an effective treatment for an incurable, sometimes life-threatening illness is within reach, the scientists said.
The study has discovered that numerous processes involved in the metastasis of melanoma, which were thought to be independent from each other, have a global coordinator: the p62 protein. The publication also discovered the involvement of another protein, FERMT2, in metastasis, and suggests that both, FEMT2 and p62, could represent indicators of bad prognosis in melanoma patients. These findings have resulted from a comprehensive analysis of clinical biopsies, new animal models and the most cutting edge -omic studies and bioinformatic methodologies.
Scientists at the University of Birmingham have discovered a protein that could hold the key to novel gene therapies for skin problems including psoriasis - a common, chronic skin disease that affects over 100 million people worldwide.