Amyloid plaque formation directly causes brain tissue loss in animals, but a drug called lithium reduces the life shortening effects of this loss, shows a new study published today in eLife.
A study of women who experienced mental ill-health from a hormonal contraception indicates they value their mental well-being higher than a satisfactory sex life. Their experiences can influence their choice of contraception. This is one of four themes that researchers have identified in interviews with 24 women who experience negative effects of some hormonal contraception. The study, from Linköping University in Sweden, has been published in the European Journal of Contraception and Reproductive Health Care.
A research team at the German Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) developed a method to isolate and cryopreserve testicular cells. This will allow the safekeeping and biobanking of gametes and other cells of the male reproductive tract of threatened or endangered feline species. The findings have been published in the scientific journal 'Cryobiology.'
Researchers led by the University of Tsukuba found that the neurotransmitter GABA is an essential regulator of metamorphosis in the sea squirt Ciona intestinalis. Larvae defective in GABA synthesis and transport failed to initiate metamorphosis and did not display adult organ growth. GABA positively regulated neurons expressing the reproductive maturation hormone GnRH, which is required for the key step of metamorphosis. These findings will help researchers to fully characterize the cellular changes underlying metamorphosis and explore pathway conservation among animals.
A chemical used in hydraulic fracturing, commonly called fracking, has the potential to interfere with reproductive hormones in men, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
Trouble for alcoholic fathers, hope for alcoholic mothers. Scientists at the University of California, Riverside, have explored the relationship between parental alcohol consumption -- before conception in the case of fathers and during pregnancy in the case of mothers -- and offspring development.
According to a new study, Zebra Finches exposed to low levels of environmental PCBs as nestlings show changes in breeding behavior as adults.
Sepsis is a life-threatening condition that kills millions annually; it is poorly understood and has no specific treatment. Now, researchers from Tata Memorial Centre, India, led by Prof. Dr Indraneel Mittra, have uncovered an important molecular mechanism underlying different aspects of sepsis--chromatin released by dying host cells after infection or injury. The scientists also put forth a novel treatment strategy for sepsis, which targets cell-free chromatin.
The conversion of skin cells into brain cells relies on proper insertion of L1 elements.
Researchers led by Jeremy Wang of the University of Pennsylvania School of Veterinary Medicine have identified an enzyme essential for the process of male meiosis, the type of cell division that produces sperm. The protein, SKP1, controls one of the key transitions in meiosis. Understanding its role may help scientists develop new approaches to treating male infertility.