Chemicals found in a variety of routinely used consumer products may be contributing to the substantial drop in sperm counts and sperm quality among men in recent decades, a new study in mice suggests.
New research in mice provides an explanation for how exposure to the widely used chemical bisphenol A (BPA) during pregnancy, even at levels lower than the regulated 'safe' human exposure level, can lead to altered brain development and behavior later in life. The research will be presented Monday, March 19 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.
A Syracuse University engineering team has developed a process that combines biomaterials-based cell patterning and stem cell technology to make a 3-D tissue model that could mimic early stage human heart development. Embryotoxicity is just one potential use of the modeling platform.
The achievements of three girls who received intensive therapy through the Virginia Tech Carilion Research Institute's Neuromotor Research Clinic based on innovative pediatric neurorehabilitation research have been documented in a report published in BMC Research Notes.
From the second trimester of pregnancy, the future baby already shows signs of pain when given a harmful stimulus or as a response to stress. In response to this confirmation, the researchers indicate the need to anesthetize the fetus during open fetal surgery, OFS.
Many tame domesticated animals have a different appearance compared to their relatives in the wild, for example white patches in their fur or shorter snouts. UZH researchers have now for the first time shown that wild house mice develop the same visible changes -- without selection, as a result of exposure to humans alone.
The journal Science published the research by biologists at Emory University, showing that a process known as hemimethylation plays a role in looping DNA in a specific way. The researchers also demonstrated that hemimethylation is maintained deliberately -- not through random mistakes as previously thought -- and is passed down through human cell generations.
Honeybee larvae develop into queen bees if they are fed large quantities of a food called royal jelly. But royal jelly does more than determine whether a larva becomes a queen: it also keeps her safely anchored to the roof of the queen cell in which she develops. Research published in Current Biology on March 15 explains how the pH of royal jelly helps make the substance viscous enough to keep the queen-to-be from falling.
Researchers at the University of Pennsylvania set out to determine whether and how gum-derived stem cells play a role in accelerated wound healing. Their results, indicating that these cells secrete tiny vesicles packed with signaling proteins, point the way forward for therapeutic strategies that aim to harness the prowess of stem cells to treat delayed wound healing as well as other conditions that involve an overactive inflammatory response, such as autoimmune diseases.
Thanks to a study conducted in pregnant women and their unborn children during the Zika epidemic in the French territories in the Americas, researchers from Inserm, Institut Pasteur and the University Hospital of Guadeloupe have been able to accurately estimate the risk of severe neurological complications in babies. They have also determined that the first trimester of pregnancy is the period which presents the highest risk. This research has been published in NEJM.