Early-life obesity and depression may be driven by shared abnormalities in brain regions that process rewards, according to researchers at the Stanford University School of Medicine.
What we eat plays a significant role in our health. The Experimental Biology 2018 meeting (EB 2018) will showcase new research into how diet could be used to fight cancer and how specific eating patterns can encourage weight loss.
Increased awareness of the health consequences of eating too much sugar has fueled a dramatic uptick in the consumption of zero-calorie artificial sweeteners in recent decades. However, new research finds sugar replacements can also cause health changes that are linked with diabetes and obesity, suggesting that switching from regular to diet soda may be a case of 'out of the frying pan, into the fire.'
Fat cells can be damaged in a short amount of time when they are exposed to the fatty acid palmitate or the hormone TNF-alpha through a fatty diet, a new study shows. The researchers from Novo Nordisk Foundation Center for Basic Metabolic Research hope this new knowledge may be used to develop new preventive strategies for diabetes.
Scientists have re-created brain neurons of obese patients using 'disease in a dish' technology, offering a new method to study the brain's role in obesity and possibly help tailor treatments to specific individuals.
A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression. This mechanism includes potential targets for next-generation drug discovery efforts to treat metabolic diseases including diabetes and obesity.
US scientists have successfully generated hypothalamic-like neurons from human induced pluripotent stem cells (hiPSCs) taken from the blood and skin cells of super-obese individuals and people with a normal body weight. The researchers found that the brain cells derived from the super obese were more likely to dysregulate hormones related to feeding behavior and hunger, as well as obesity-related genes and metabolic pathways. The work appears April 19 in the journal Cell Stem Cell.
People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers. They found that people with obesity had a 40 percent higher chance of developing atrial fibrillation than people without obesity.
A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger.
Cruelly, the gene is sex specific: men with the same variation of the gene have a much less heightened diabetes risk.