University at Buffalo researchers have developed 3-D printed dentures filled with antifungal medication to better treat oral fungal infections.
Recently, a team of researchers designed a study to learn more about cognitive health and older drivers' crash risks. The study, published in the Journal of the American Geriatrics Society, focused on links between levels of cognitive function and crash risk among older drivers without dementia over a 14-year study period. They also assessed the link between changes in cognitive function over time and later risks of crashes.
The rabies virus wreaks havoc on the brain, triggering psychosis and death. To get where it needs to go, the virus must first trick the nervous system and cross the blood brain barrier -- a process that makes it of interest in drug design. Now, scientists report in ACS Nano a way to exploit the rabies virus machinery to deliver a Parkinson's disease medication directly to the brain.
The largest and most detailed study of the long-term impact of anticholinergic drugs, a class of drugs commonly prescribed in the United States and United Kingdom as antidepressants and incontinence medications, has found that their use is associated with increased risk of dementia, even when taken 20 years before diagnosis of cognitive impairment.
According to Finnish longitudinal cohort study, the amount of sitting during free time increases after transitioning to retirement. In general, sedentary behavior is known to be associated with several health issues.
Long-term use of some anticholinergic medications are associated with an increased risk of dementia -- according to a new study led by the University of East Anglia (UK).
Telomerase, because of its role in cancer and aging, has long been a target of drug companies who want to block it to stop the uncontrolled cell growth characteristic of cancer, or boost it to create a fountain of youth. The structure of the enzyme complex has been a mystery, however, until now. UC Berkeley scientists have finally obtained a detailed picture of the architecture of the RNA-protein complex, a breakthrough for drug design.
After a heart attack, patients must create new heart muscle cells to heal. Harvard study shows that mice make more new heart muscle cells when they exercise compared to when they do not. This was true for both healthy mice and those that had experienced a heart attack. Findings demonstrate that one reason exercise is beneficial to health is that it increases the heart's capacity to regenerate.
Age and older adults are largely obscured in media representations of cancer, according to a study published in the open-access journal BMC Public Health. It is important that older adults appreciate their heightened risk of cancer, as a lack of awareness may have a negative impact on early presentation and detection, a team of researchers led by the University of Glasgow Institute of Health and Wellbeing suggest.
Researchers at the University of Exeter have found a statistical link between pneumonia in older people and a group of medicines commonly used to neutralize stomach acid in people with heartburn or stomach ulcers. Although proton-pump inhibitors (PPIs) are still a valuable group of medicines, research is indicating that PPIs are not as completely safe for older people as previously thought.