News by Subject Medicine & Health

Estrogen has a significant role in overall brain health and cognitive function. That's why so many studies focused on the prevention of cognitive decline consider the effect of reduced estrogen levels during the menopause transition. A new study suggests a cognitive benefit from a longer reproductive window complemented with hormone therapy. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).

In a study published in the Journal of the American Geriatrics Society, researchers examined information from the European Project on OSteoArthritis (EPOSA) study. They wanted to learn whether there is an association between arthritis and social isolation, and to identify the disease's contribution to social isolation.

Despite the evidence on risk factors for frailty, and the substantial progress that has been made in frailty awareness, the biological mechanisms underlying its development are still far from understood and translation from research to clinical practice remains a challenge. A new paper provides an up-to-date clinical overview on preventing, identifying and managing frailty as well as its global impact and burden.

The UConn Health study followed 199 hypertension patients 75 years of age and older for 3 years.

The UK Government is at risk of missing its target to increase healthy life expectancy by five years by 2035, according to a new report, Growing Older, Better, published by The Physiological Society on Tuesday Oct. 15, 2019.

Researchers have discovered new changes in blood samples associated with Alzheimer's disease. A new international study was conducted on disease-discordant Finnish twin pairs: one sibling suffering from Alzheimer's disease and the other being cognitively healthy. The researchers utilised the latest genome-wide methods to examine the twins' blood samples for any disease-related differences in epigenetic marks which are sensitive to changes in environmental factors. These differences between the siblings were discovered in multiple different genomic regions.

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD), adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.