Until now, little was known about the effects of dementia on early hospital readmission. Researchers in Japan recently published the results of a study to learn more about the effects of dementia and being admitted to the hospital within 30 days of a previous hospital discharge (the medical term for leaving the hospital once your care is considered complete). Their study was published in the Journal of the American Geriatrics Society.
As we grow older, our muscular function declines. A new study by researchers at Karolinska Institutet in Sweden shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration. This discovery may result in new medication to build stronger muscles even when in old age. The study is published in Nature Communications.
Johns Hopkins scientists invent multifunctional antibody-ligand traps (Y-traps), a new class of cancer immunotherapeutics. They develop Y-traps comprising an antibody targeting an immune checkpoint (CTLA-4 or PD-L1) fused to a TGFβ trap. In humanized mouse models, these Y-traps reverse immune suppression and inhibit growth of tumors that do not respond to current immune checkpoint inhibitors.
A UCLA study explored the relationship between new drivers' skills and age, gender, organized sports and video gaming. The results suggest that mandatory training should be required for all novice drivers, not just teenagers.
Princeton researchers identified a key protein in old, poor-quality C. elegans eggs. When they blocked this protein midway through the fertile window, the equivalent of a woman in her early thirties, they successfully extended egg viability beyond the normal span. Another experiment that knocked out this protein's genes entirely extended the worms' fertility by about 10 percent. If applied to humans, that could represent a 3- to 6-year extension of female fertility.
This massively-collaborative research proposes the roadmap for making humans more resistant to radiation and multiple other forms of stress- and age-associated damage.
Tears may hold clues to whether someone has Parkinson's disease, according to a preliminary study released today that will be presented at the American Academy of Neurology's 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.
Previous studies with older NFL football players have found a high incidence of sleep apnea, a serious health issue, among the group, particularly among older linemen. Now, a study with college-age linemen suggests that the roots of this health problem in football players may begin much earlier, and at an age when the condition is much less likely to occur in the general population. Body training specific to linemen appears to be related.
A team of researchers from Belgium recently studied how people with Alzheimer's disease use medical services during their final months. The goal was to learn more about the best ways to help older adults with dementia at the end of their lives. Their study was published in the Journal of the American Geriatrics Society.
For couples with decades of shared memories, a partner's decline in the ability to communicate because of dementia is frightening and frustrating. Communication strategies they've used before simply don't work anymore. By getting creative, an in-home intervention to support couples affected by dementia is showing that 'practice does make perfect,' both for the caregiver and the care receiver or person with dementia, and can improve their communication behaviors in just 10 weeks.