The drug hydroxyurea does not appear to increase the risk of malaria infection in patients with sickle cell anemia who live in malaria-endemic regions, according to a study published online today in Blood, the Journal of the American Society of Hematology (ASH).
Using a computational approach known as deep learning, scientists have developed a new system to classify the shapes of red blood cells in a patient's blood. The findings, published in PLOS Computational Biology, could potentially help doctors monitor people with sickle cell disease.
The FDA today approved the use of a breakthrough cancer treatment for adult patients with relapsed or refractory diffuse large B-cell lymphoma, a form of non-Hodgkin lymphoma. The treatment is a form of CAR T-cell therapy now labelled Yescarta (axicabtagene ciloleucel). The University of Chicago Medicine is the first site in Illinois certified by both Kite Pharma Inc. and Novartis.
Blood samples taken by first responders showed that individuals exposed to small amounts of oil from the spill suffered from hemolytic anemia--a condition that occurs when toxins enter the blood stream and damage red blood cells that carry oxygen to tissues.
Among patients who received red blood cell transfusions, receiving a transfusion from a donor who was ever pregnant, compared with a male donor, was associated with an increased risk of death among male recipients of transfusions but not among female recipients, according to a study published by JAMA
Giving hope that his treatment may work in humans, Vance G. Nielsen, M.D., of the University of Arizona College of Medicine -- Tucson, has published results showing his carbon monoxide-iron-based therapy can inhibit snake venom's effects for up to an hour in animals. The treatment eventually could be delivered with a device similar to an EpiPen autoinjector and stocked on ambulances and in first-aid kits.
New research published today uncovers how the blood cancer 'steals' parts of surrounding healthy bone marrow cells to thrive, in work that could help form new approaches to cancer treatment in the future. Researchers at the University of East Anglia (UEA), funded by the Rosetrees Trust and The Big C Charity, found that healthy bone marrow stromal cells were made to transfer their power-generating mitochondria to neighbouring cancer cells, effectively 'recharging' the acute myeloid leukaemia (AML) and supporting the leukaemia to grow.
Women who develop high blood pressure in their 40s may be more likely to develop dementia years later, according to a study published in the Oct. 4, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Healthcare experts have long known the benefits of integrated sepsis care programs, yet less information has been published on potential unintended consequences of these programs. That's changed with a new study that suggests that electronic sepsis screenings and treatment protocols could, in fact, lead to increased use of certain broad-spectrum antibiotics and healthcare facility-onset (HCFO) C. difficile infection (CDI) rates, according to findings published in the October issue of the American Journal of Infection Control (AJIC).
Users of statins, widely prescribed for prevention of cardiac disease, have a 27% lower risk of contracting a Staphylococcus aureus (S aureus) bloodstream infection outside of a hospital, according to a new study in Mayo Clinic Proceedings. Researchers report that statin use, especially among elderly patients with preexisting chronic conditions such as diabetes, kidney, or liver disease, may be protective against this serious bloodstream infection.