A study based at the Ragon Institute of MGH, MIT and Harvard has determined how a pregnant woman's vaccine-induced immunity is transferred to her child, which has implications for the development of more effective maternal vaccines.
Researchers from the University of Oxford, along with partners from five institutions around the world, have identified the human antibodies that prevent the malaria parasite from entering blood cells, which may be key to creating a highly effective malaria vaccination. The results of the study were published today in the journal Cell.
Duke researchers describe a previously unidentified route for antibodies to be transferred from the mother to the fetus, illuminating a potential way to capitalize on this process to control when and how certain antibodies are shared.
Vaccinating babies against a virus that causes childhood 'stomach flu' greatly reduces their chance of getting so sick that they need hospital care, a new study shows. But the study also reveals a surprise: Getting fully vaccinated against rotavirus in the first months of life is associated with a lower risk of developing Type 1 diabetes later on.
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019), jointly organized with the Paediatric Rheumatology Society (PReS), demonstrate no vaccine infections, and no disease flare, in the 234 rheumatic patients who received live-attenuated booster vaccination while taking immune suppressing therapies.
A unique adjuvant, a substance that enhances the body's immune response to toxins and foreign matter, can prevent vaccine-enhanced respiratory disease, a sickness that has posed a major hurdle in vaccine development for respiratory syncytial virus (RSV), according to a study led by the Institute for Biomedical Sciences at Georgia State University.
Researchers at CSHL used cryo-EM and computational tools to reconstruct the shell structures of four different strains of human noroviruses. Deciphering this can help inform future vaccine developments against the virus.
Researchers at CDDEP, the University of California, Riverside and Harvard T.H. Chan School of Public Health assessed the long-term associations of the Hib vaccine with anthropometric, cognitive, and schooling outcomes among Indian children.
An international group of researchers has found that antibodies to the human papillomavirus type 16 (HPV16) develop in the body between six to 40 years prior to a clinical diagnosis of throat cancer, and their presence indicates a strong increased risk of the disease. The study is published in Annals of Oncology.
A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations. The findings, appearing June 11, 2019 in the journal Cell Reports, may inform the development of new vaccine strategies and could lead to personalized vaccination schedules to maximize vaccine effectiveness.