Scientists at the Joint Research centre, the European Commission's science and knowledge service, simulated real-world social networks to assess the best strategies for halting epidemics.
New research shows that all-trans-retinoic acid (atRA), the active form of vitamin A, regulates immune system responses in the mouse intestine by controlling expression of the protein HIC1 in cells known as innate lymphoid cells. These findings, which could suggest new ways to fight disease, are presented in PLOS Pathogens by Dr Kyle Burrows of the University of British Columbia, Canada, and colleagues.
Scientists have found and characterized the activity of four antibodies produced by the human immune system that target an important protein found in respiratory syncytial virus (RSV), according to new research published in PLOS Pathogens.
Researchers from the University of Chicago, Harvard University and others show that poor immune responses, not egg adaptions, may explain the low effectiveness of the vaccine that year.
Aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (TB), today announced results from an innovative clinical trial that provides encouraging new evidence that TB vaccines could prevent sustained infections in high-risk adolescents. In a prevention-of-infection Phase 2 trial conducted in South Africa, revaccination with the Bacille Calmette-Guerin (BCG) vaccine significantly reduced sustained TB infections in adolescents. An experimental vaccine candidate, H4:IC31, also reduced sustained infections, although not at statistically significant levels.
Stanford University researchers report that injecting mice with inactivated induced pluripotent stem cells (iPSCs) launched a strong immune response against breast, lung, and skin cancers. The vaccine also prevented relapses in animals that had tumors removed. The work appears in the journal Cell Stem Cell on Feb. 15.
Scientists are now equipped with a more detailed picture of the human immune system's response to influenza vaccination, thanks to the results of a new investigation.
Scientists at The Scripps Research Institute (TSRI) have achieved a major milestone toward designing a safe and effective vaccine to both treat heroin addiction and block lethal overdose of the drug.
New injectable delivery system forms a non-inflammatory depot that can continuously release drug carriers for months at a time after a single administration.
Analysis of more than 38,000 children in Ghana shows that all-cause mortality is significantly lower in children who received the measles vaccine after the third diphtheria-tetanus-pertussis (DTP) vaccination. The study adds to growing evidence that, when administered in the WHO recommended sequence, measles vaccination provides non-specific benefits to child survival. The findings have implications for achieving the Millennium Development Goal 4 of reducing child mortality.