Using laboratory equipment readily available in developing countries, researchers from UNC and Abbott Diagnostics were able to define and map the burden of hepatitis C virus for the first time in the Democratic Republic of the Congo. Their findings were published in Clinical Infectious Diseases.
Scientists have for the first time shown that a novel compound effectively suppresses production of the virus in chronically infected cells.
Nearly half of all US medical care is delivered by emergency departments, according to a new study by researchers at the University of Maryland School of Medicine. In recent years, the percentage of care delivered by emergency departments has grown. The paper highlights the major role played by emergency rooms in US health care.
Massachusetts General Hospital investigators have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with the hepatitis C virus who develop chronic infection from those whose immune systems successfully clear the virus.
Many health care providers in China -- especially those at village clinics and township health centers -- fail to correctly manage tuberculosis (TB) cases, according to a study involving standardized patients published this week in PLOS Medicine by Sean Sylvia of the University of North Carolina at Chapel Hill, USA, Chengchao Zhou of Shangdong University, China, and colleagues at the World Bank, McGill University, Stanford University and other institutions in China.
An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a condition known as elephantiasis. Scientists at Washington University School of Medicine in St. Louis have shown that a portable scanning device can measure limb enlargement and disfigurement faster and more easily in patients with elephantiasis. The research tool makes it easy to obtain accurate measurements and determine whether treatments to reduce swelling are effective.
Arteriviruses, a family of single-stranded RNA viruses that belongs to the order Nidovirales, produce more proteins and messenger RNAs than previously reported, a finding that provides important insights about a virus that could potentially evolve to infect humans in the future, according to a new research study.
The endogenous infection marker procalcitonin can help to guide the use of antibiotics when treating infections. The course of antibiotic therapy is shortened, and its side effects and mortality rate also decrease, as researchers from the University of Basel and other colleagues report in the journal The Lancet Infectious Diseases. They conducted a meta-analysis of over 6,700 international data sets from patients with respiratory infections.
Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA and the results are published in the scientific journal Microbiome.
During 10 subsequent years no Usutu virus associated bird mortality was observed in Austria - contrary to neighboring Hungary. Last year Usutu virus was identified again in two blackbirds - and in 2017 already in sixteen songbirds. A research team of the Vetmeduni Vienna investigated the virus strains involved. In another study Usutu virus was demonstrated in seven human blood donations from eastern Austria, suggesting that human infections seem to be more frequent than previously thought.