The National Academies of Sciences, Engineering, and Medicine today released proceedings of a March 12 workshop exploring the rise in infectious diseases accompanying opioid abuse, and possible strategies for reducing both epidemics.
In this article, together with a review of the literature, we report two cases of imipenem-resistant Acinetobacter baumannii neonatal meningitis following ruptured myelomeningocele, treated with intravenous colistin with favorable results.
A Yale-led team of researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine that works by targeting the specific protein that parasites use to evade the immune system. The study was published by Nature Communications.
Thirteen patients with OXA-48-producing Klebsiella pneumoniae ST392 have been reported by Sweden and Norway between January and April 2018 -- all returning travelers with prior hospital admission in Gran Canaria. Whole genome sequencing showed tight clustering between the bacterial isolates from the cases.
Findings from an animal study suggest that a non-invasive imaging technique could, with further development, become a tool to assess immune system recovery in people receiving treatment for HIV infection. Researchers used single-photon emission computed tomography (SPECT) and a CD4-specific imaging probe to assess immune system changes throughout the bodies of macaques infected with SIV following initiation and interruption of antiretroviral therapy (ART). They evaluated pools of CD4+ T cells in tissues.
When a cell divides, its constituents are usually evenly distributed among the daughter cells. UZH researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed. Their discovery opens up new opportunities for the treatment of cancer, neurodegenerative diseases, aging processes and viral infections.
New research has uncovered a protein enabling the replication of arenaviruses, pathogens now widespread in West Africa that are carried by rodents and can infect humans with lethal fevers. The research identified DDX3 as a key factor promoting arenavirus multiplication through its unexpected ability to promote viral RNA synthesis and dismantle normal human immune system defenses. The study may pave the way to new therapeutic treatments for arenaviruses and hemorrhagic fever.
A new scientific study finds 93 people live in remote areas with venomous snakes and, if bitten, face a greater likelihood of dying than those in urban settings because of poor access to anti-venom medications.
A nationwide investigation of the prevalence and distribution of ticks and exposure to tick-borne diseases highlights the value of public participation in science. The study, published on July 12 in the open-access journal PLOS ONE, was conducted by Nathan Nieto of Northern Arizona University and colleagues, and funded by Bay Area Lyme Foundation.
Countries have traditionally been divided into two broad categories according to their capacity to innovate. Now, researchers reporting in PLOS Neglected Tropical Diseases say these categories are overly simplistic and leave out the key roles that a group of Innovative Developing Countries (IDCs) play in the public health arena.