To treat Candida albicans, a common yeast that can cause illness in those with weakened immune systems, University at Buffalo researchers limited the fungus' access to iron, an element crucial to the organism's survival.
Dengue, also known as dengue fever, is a viral disease transmitted to humans by mosquitoes of the genus Aedes. The incidence of dengue is currently increasing dramatically, and it is now one of the diseases said to be re-emerging. Researchers at the Institut Pasteur have conducted a study to determine the burden of dengue in Bangladesh and identify key risk factors for infection.
A commentary by researchers addresses the specter of clinical, ethical, public health and legal concerns that have been raised because of the recent measles outbreaks in New York. So far, the outbreaks seem to have emanated from ultra-Orthodox Jewish residents whose affected children were never vaccinated. Their commentary is motivated in part by the availability of important and relevant data from a small case series of interviews conducted with ultra-Orthodox Jewish mothers in Williamsburg and Rockland counties.
The most severe pandemic in recent history, killing some 50 million people worldwide, the Spanish influenza, may have emerged up to two years earlier than previously believed. And, according to a new and influential study, its early manifestation was ignored at the time as a 'minor infection.'
Leptospirosis is an emerging zoonotic disease that affects more than one million people around the world each year. Researchers reporting in PLOS Neglected Tropical Diseases have now sequenced the genomes of Leptospira collected from environments around the globe and revealed 30 new species and new patterns of species diversity.
Researchers show that procedures used to contain Candida auris infection in an animal facility can potentially be applied to hospitals and nursing homes to limit its spread.
Computational modeling of social networks suggests that vaccination programs are more successful in containing disease when individuals have access to local information about disease prevalence. Anupama Sharma of The Institute of Mathematical Sciences in Chennai, India, and colleagues present these findings in PLOS Computational Biology.
A team of scientists of the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal, Canada , has tackled this fundamental question and recently identified a target to 'tone down' the hyper-active immunity to influenza infection. These novel findings have promising clinical implications in the near future for the treatment of flu.
A protein from Simian Immunodeficiency Virus (SIV), which can infect monkeys and apes, has shown promise as a potential component of a vaccine against Human Immunodeficiency Virus (HIV), in a new study from scientists at Scripps Research.
A new study based on a mostly forgotten guide to medicinal plants, 'Resources of the Southern Fields and Forests,' focuses on three of the plants and shows they inhibit bacteria associated with wound infections.