Brazil runs a serious risk of being afflicted by Oropouche, another virus that is widely distributed throughout South and Central America and the Caribbean. An arbovirus transmitted by a mosquito (like Zika and yellow fever), Oropouche causes acute fever and may lead to meningitis and meningoencephalitis (inflammation of the brain and meninges).
NIH scientists have filled a research gap by developing a laboratory model to study ticks that transmit flaviviruses, such as Powassan virus. Powassan virus was implicated in the death of a New York man earlier this year. The unusual model involves culturing organs taken from Ixodes scapularis ticks and then infecting those organ cultures with flaviviruses, according to researchers at Rocky Mountain Laboratories, part of NIH's National Institute of Allergy and Infectious Diseases.
For the first time, researchers are using proteomics to examine proteins and peptides in saliva in order to accurately detect exposure to Zika virus. With 70 countries and territories reporting evidence of mosquito-borne Zika virus transmission, there is an increased need for a rapid and effective test for the virus. This study, published online today in the Journal of Dental Research (JDR), offers a new, quicker and more cost-effect way to test for the virus.
Scientists have pinpointed how a tiny protein seems to make the deadly Ebola virus particularly contagious.
University at Buffalo researchers have assembled a team of three antibiotics that, together, are capable of eradicating E. coli carrying mcr-1 and ndm-5 -- genes that make the bacterium immune to last-resort antibiotics.
Researchers have revealed the existence of a new quorum-sensing molecule that increases the virulence of the pathogenic bacterium Pseudomonas aeruginosa.
New research, conducted by the University of Liverpool and Liverpool School of Tropical Medicine, highlights the need for long-term rehabilitation of Ebola survivors after almost 80 percent of those interviewed were found to have major limitations in mobility, cognition and vision.
A recent study published in Frontiers in Cellular and Infection Microbiology presents a comprehensive overview of S. aureus' remarkable resilience against our body's immune system and how to better protect against deadly infections, with implications for overcoming antibiotic resistance.
Duke scientists found a gene variant that affects cholesterol levels also could increase the risk of contracting typhoid fever. A common cholesterol-lowering drug could protect animal models against Salmonella Typhi, the culprit behind the potentially deadly infection. The findings give insight into the mechanisms that govern human susceptibility to infectious disease and point to possible avenues to protect against pathogens -- like Salmonella or Ebola -- whose entry into host cells is regulated by cholesterol.
The Zika virus suppresses a pregnant woman's immune system, enabling the virus to spread and increasing the chances an unborn baby will be harmed, study finds. The study is the first to report that the Zika virus targets specific white blood cells, handicapping a pregnant woman's immune system in a way that almost resembles HIV. Pregnant women are more prone to immune suppression. Zika exploits that weakness to infect and replicate.