Gut bacteria at a young age can contribute to multiple sclerosis disease onset and progression.
UNC School of Medicine researchers have developed a new laboratory model to measure and compare the responses of CF and normal airway cells to CF-related infectious/inflammatory factors.
While genetics play a role in the development of Lupus, a systemic autoimmune disease, so do environmental triggers, such as particulates in air pollution and ultraviolet light, says a University of Cincinnati researcher.
A new roundtable report from the Institute for Scientific Information on Coffee (ISIC) in association with the British Liver Trust, on 'Looking after the liver: coffee, caffeine and lifestyle factors' highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis, with some studies reporting risk reduction of up to 70%
Researchers have uncovered a sequence of biological processes that occur in humans infected with the bacterium Mycobacterium tuberculosis as the infection progresses to pulmonary tuberculosis, according to new research published in PLOS Pathogens.
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Amish living in Indiana, reports a new study. An experimental 'longevity' drug that recreates the effect of the mutation is now being tested in human trials to see if it provides protection against aging. Indiana Amish with the mutation live 10 percent longer, are protected from diabetes and have a younger cardiovascular system.
Ganesh Halade, who uses a mouse heart attack model to research ways to prevent heart failure, has published a functional and structural compendium of the simultaneous changes taking place in the heart, spleen and kidneys in mice during the period of acute heart failure immediately following a heart attack and during the longer period of chronic heart failure that comes next.
Discontinuity of care puts older patients at higher risk of emergency hospitalization.
A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis -- scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.
By focusing on genetic variations within a primary tumor, differences between the primary and a metastatic tumor, and additional diversity from tumor DNA in the blood stream, physicians can make better treatment choices for patients with gastric and esophageal adenocarcinoma. This study challenges current guidelines and supports evaluation of metastatic lesions and circulating tumor DNA.