Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma. In a study of over 200 participants with severe asthma, the new treatment was shown to have improved asthma symptoms and lung function, while reducing the need for corticosteroids by up to 70%.
A team of scientists led by University of Montana cell biologist Mark Grimes has identified networks inside lung cancer cells that will help understand this cancer and fight it with drug treatments.
Before invading the bloodstream, the malaria-causing Plasmodium parasite rapidly reproduces inside its host's liver cells. Duke University researchers show that liver-stage Plasmodium relies on a host protein called aquaporin-3 to survive and copy itself. Inhibiting the function of aquaporin-3 may provide a new way to keep Plasmodium from proliferating and prevent malaria before symptoms start.
Prescription cough and cold medicines containing the opioid hydrocodone were more likely to cause serious side effects in children than those containing codeine, according to a new study from Penn State College of Medicine. The research supports recent U.S. Food and Drug Administration (FDA) restrictions on prescription hydrocodone- and codeine-containing cough medicines for children and suggests that opioids in general should not be prescribed for coughs and colds in pediatric populations.
Medical students seldom learn much about the real-life problems (hunger, joblessness, addiction) their patients face outside the clinic walls. Yet, these problems are at the root of poor health in many low-income communities. An article published today describes a new course which apprentices medical students to community health workers (CHWs) in inner city Philadelphia. CHWs are trusted laypeople who come from the local community, hired and trained by healthcare organizations to support high-risk patients.
Ingestion of a blue dye tablet during bowel prep for colonoscopy could be a significant advance in the early detection of colorectal cancer (CRC). When used in conjunction with colonoscopy, the blue dye increased adenoma detection rate (ADR) by nearly 9 percent, according to a study scheduled for presentation at Digestive Disease Week® (DDW) 2018.
Increasingly, liver transplant centers are changing a long-standing practice of delaying potentially life-saving liver transplantation for patients with severe alcoholic hepatitis until after they stopped drinking alcohol for six months, according to a new study scheduled for presentation at Digestive Disease Week® (DDW) 2018.
Combining a DNA vaccine, which boosts the body's immune response against tumors, with an antibody that blocks the body's natural defense against the potency of the DNA vaccine, may lead to the development of an effective treatment for late stage colorectal cancer, when a cure is not often possible. Preliminary research leading up to this trial will be presented at Digestive Disease Week® 2018.
An investigational new drug offers hope of relief for celiac disease patients who are inadvertently exposed to gluten while on a gluten-free diet. Findings of the first phase 2 study of a biologic immune modulator in celiac disease will be presented at the upcoming Digestive Disease Week® (DDW) 2018. Inadvertent exposure to gluten can be a frequent occurrence for celiac patients that triggers symptoms, such as pain in the gut and diarrhea, due to intestinal damage.
Black infants born preterm who received sustained vitamin D supplementation had a lower likelihood of recurrent wheezing by age 1.