Scientists created human pancreas on a chip that allowed them to identify the possible cause of a frequent and deadly complication of cystic fibrosis (CF) called CF-Related Diabetes, or CFRD. It may be feasible to also use the small two-chambered device, which features bioengineered human pancreatic organoids to study the causes of non-CF-related conditions such as type 1 and 2 diabetes, according to researchers who report findings in Nature Communications.
One of the most commonly performed surgeries to treat stress urinary incontinence in women may have better long-term results than another common surgical technique, according to a study led by Mayo Clinic researchers. The retrospective study of more than 1,800 cases at Mayo Clinic from 2002 to 2012 found that the need for additional surgery was twice as high after a transobturator sling surgery compared with a retropubic sling procedure.
University of Colorado Cancer Center study published in Breast Journal argues against combined approach: Patients undergoing coordinated breast and gynecologic procedures had a significantly longer length of hospital stay, and higher complication, readmission, and reoperation rates compared with patients who underwent single site surgery.
An Australian study has demonstrated that cannabis-based medication helps tackle dependency on cannabis, one of the most widely used drugs globally. A paper about the University of Sydney and NSW Health clinical trial provides the first strong evidence that cannabis replacement therapy could reduce the rate of relapse. The principles are similar to nicotine replacement in that the patient is provided a safer drug and in an environment that helps break the pattern of use.
An observational study based on a group of smokers and former smokers in France looked at whether electronic cigarette use was associated with changes in the number of cigarettes smoked, with smoking cessation rates among smokers, and with smoking relapse among former smokers.
Patients who underwent cold snare polypectomy for small polyps while continuing to take anticoagulants did not experience increased incidence of severe bleeding compared with those who underwent hot snare polypectomy with heparin bridging. Findings from a multicenter, randomized, controlled trial are published in Annals of Internal Medicine.
Many burn victims suffer acute kidney injury, but early recognition of the condition can be challenging. Now an Artificial Intelligence / Machine Learning model developed at UC Davis Health and reported in a new study can predict acute kidney injury quicker and more accurately than ever.
New research from UPMC and Pitt shows that living-donor liver transplant offers numerous advantages over deceased-donor transplant, including superior outcomes and less resource utilization.
Researchers from Clemson University's Environmental Toxicology Program have published research connecting an enzyme associated with detoxification to obesity and fatty liver disease, especially in males.
Adolescent girls who reach puberty at an earlier age may also have a greater chance of developing migraine headaches, according to new research from investigators at the University of Cincinnati (UC) College of Medicine.