Researchers have discovered that genetic variations in the anatomy of the lungs could serve as indicators to help identify people who have low, but stable, lung function early in life, and those who are particularly at risk for chronic obstructive pulmonary disease (COPD) because of a smoke-induced decline in lung function.
Wearable biosensors have grown increasingly popular as many people use them in wristbands or watches to count steps or track sleep. But there is not enough proof that these devices are improving patient outcomes such as weight or blood pressure, according to a study by Cedars-Sinai investigators published in the new Nature Partner Journal, npj Digital Medicine.
Roughly 10 percent of nitrogen-fixing microorganisms contain the genetic code for manufacturing a back-up enzyme, called iron iron-only nitrogenase, to do their job. New research reveals that this enzyme allows these microorganisms to convert nitrogen gas to ammonia and carbon dioxide into methane at the same time. This enzymatic pathway is a previously unknown route for the natural biological production of methane.
Normal tissue BRCA1 methylation is associated with risk for high-grade ovarian cancer and may occur as a prenatal event. These findings are published in Annals of Internal Medicine.
The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades.
Researchers have demonstrated the potential of a new class of drugs for the treatment of refractory chronic obstructive pulmonary disease, i.e. COPD. Incurable to date, the disease is one of the most frequent causes of death worldwide and is typically triggered by smoking. In the current preclinical study, two anti-inflammatory substances have proved more effective than preparations used to date. The results were published in the Journal of Allergy and Clinical Immunology.
Asthma costs the US economy more than $80 billion annually in medical expenses, missed work and school days and deaths, according to new research published online in the Annals of the American Thoracic Society.
Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists. Defects in the fungus-fighting abilities of these cells may contribute to some cases of Crohn's disease and other forms of inflammatory bowel disease (IBD).
When babies crawl, their movement across floors, especially carpeted surfaces, kicks up high levels of dirt, skin cells, bacteria, pollen, and fungal spores, a new study has found. The infants inhale a dose of bio bits in their lungs that is four times (per kilogram of body mass) what an adult would breathe walking across the same floor.
A new article publishing in the forthcoming volume of the Annual Review of Public Health focuses on harm minimization and smoking cessation, with alternative nicotine products like e-cigarettes emerging as a promising avenue for people who want to quit smoking.