In this article, together with a review of the literature, we report two cases of imipenem-resistant Acinetobacter baumannii neonatal meningitis following ruptured myelomeningocele, treated with intravenous colistin with favorable results.
A new way to examine stress and inflammation in the heart will help Parkinson's researchers test new therapies and explore an unappreciated way the disease puts people at risk of falls and hospitalization.
Experts are drawing on lessons learned from the early days of the HIV epidemic to address the current opioid epidemic. As a result of widespread opioid abuse, new epidemics of hepatitis C virus (HCV) and HIV infection have arisen and hospitalizations for related infections have increased. An expert panel convened by the National Academies of Sciences, Engineering, and Medicine (NASEM) recommends five crucial steps for clinicians treating patients affected by opioid addiction and these intersecting infections.
Heavy drinking causes iron loading which puts strain on vital organs, research finds.
A review of more than 200 studies reveals that olfactory receptors -- proteins that bind to odors that aid the sense of smell -- perform a wide range of mostly unknown functions outside the nose. The function of extra-nasal olfactory receptors has the potential to be used in the diagnosis and treatment of health conditions such as cancer. The article is published in the July issue of Physiological Reviews.
A study has newly identified an immune trigger of some fibrotic diseases and an experimental compound to treat it. Fibrosis -- a progressive scarring and hardening of internal organs -- is estimated to cause 35 to 40 percent of deaths in the world.
Some patients with COPD demonstrate signs of accelerated aging. In a new study published in the journal CHEST® researchers report that measuring blood telomeres, a marker of aging of cells, can be used to predict future risk of the disease worsening or death. Further, they have determined that the drug azithromycin may help patients with short telomeres, an indicator of more rapid biological aging, stave off negative clinical outcomes.
Scientists at Kyoto University have used induced pluripotent stem cells to make platelets at numbers (> 100 billion) that can be used in the clinic. The ability comes from combining stem cell technology with bioreactors that incorporate turbulence. This artificial blood system is expected to replace blood donors for platelet transfusions.
In a new policy issued today, the American College of Physicians (ACP) stated that immigrant families who have been separated at the border should be reunited as expeditiously as possible. If genetic testing is considered appropriate, it should be done in the least intrusive manner, with safeguards and attention to medical ethics.
Virus-like particles (VLPs) are protein-based structures that mimic viruses and bind to antibodies. Because VLPs aren't infectious, they show promise as vaccine platforms for many viral diseases, including influenza. Since details about influenza VLPs are scant, a team of researchers developed a 3D model based on the 1918 H1 pandemic influenza virus. The research, conducted by NIAID scientists, could benefit VLP vaccine projects, targeting a range of viruses from HIV to Ebola and SARS coronavirus.