Research is an important component of academic medicine, but many family medicine departments have struggled with barriers ranging from departmental culture to the lack of resources needed to advance the field. A paper published in Family Medicine reports that key factors to boost the creation of knowledge include leadership commitment to research and building a team approach to research that is relevant to family medicine.
Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.
A protein with a role in sensing cell damage and viral infections is a new target for the treatment of pulmonary hypertension, or increased blood pressure in the lungs, according to research led by Virginia Commonwealth University and the University of Sheffield in the United Kingdom.
When healthy people eat a low-gluten and fiber-rich diet compared with a high-gluten diet they experience less intestinal discomfort including less bloating which researchers at University of Copenhagen show are due to changes of the composition and function of gut bacteria. The new study also shows a modest weight loss following low-gluten dieting. The researchers attribute the impact of diet on healthy adults more to change in composition of dietary fibers than gluten itself.
Children born prematurely often experience serious problems with the gastrointestinal tract and therefore have increased risk of developing life-threatening bowel infection. Now researchers from the University of Copenhagen have shown, in a study on pigs, that transplantation of faeces from healthy pigs changes the bowel's bacterial composition in those born prematurely and protects them from the fatal bowel disease necrotizing enterocolitis (NEC).
Investigating a new marker for chronic inflammation GlycA, researchers have found that chronic inflammation is linked to increased risk for shorter lifespan and several organ-related diseases. The findings were made through investigating GlycA measurements with Nightingale Health's blood testing technology. The results highlight a potential use for measuring GlycA in healthcare.
Outbreaks of norovirus in health care settings and outbreaks caused by a particular genotype of the virus are more likely to make people seriously ill, according to a new study in The Journal of Infectious Diseases. Based on an analysis of nearly 3,800 US outbreaks from 2009 to 2016, the research confirms several factors that can make norovirus outbreaks more severe and may help guide efforts to develop a vaccine to prevent this highly contagious disease.
A new study published in Clinical Kidney Journal indicates that the usage of marijuana by kidney donors has no measurable effect upon the outcomes of kidney transplants for donors or recipients. This study is the first to investigate the effect of marijuana use by live kidney donors.
New research has identified rogue cells -- namely brain and muscle cells -- lurking within kidney organoids. Such cells make up only 10 to 20 percent of an organoid's cells, but their presence indicates that the 'recipes' used to coax stem cells into becoming kidney cells inadvertently are churning out other cell types.
Patients with rare, but incurable cancers of the digestive tract have responded well to a combination of two drugs that block the MEK and BRAF pathways, which drive the disease in some cases. They have survived for longer without the disease progressing than the usual average time of less than five months, even though their cancer was advanced and had not responded to previous therapies. The research is presented at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.