New high-resolution maps pinpoint areas across Africa with concentrations of child deaths from diarrhea and show uneven progress over 15 years to mitigate the problem. The study, covering 2000 to 2015, maps the entire African continent in 5x5 square kilometer units and was published today in The New England Journal of Medicine. National and provincial maps of diarrhea in Africa often mask inequalities at the local community level, according to IHME researchers.
New University of Otago research shows infants using popular anti-reflux medicines like omeprazole are not at increased risk of pneumonia or other lower respiratory tract infections, contrary to findings from other international studies.
Our result suggests preoperative albumin level as an independent risk factor for PPCs in elderly gastric cancer (GC) patients after elective laparoscopic gastrectomy. We also suggest that those elderly hypoalbuminemic GC patients may benefit from more intensive perioperative care including perioperative nutritional status improvement.
Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders -- including ulcerative colitis and Crohn's disease -- remains a clinical challenge. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), in collaboration with scientists at Technion - Israel Institute of Technology, have identified a protein that drives intestinal inflammation. This finding highlights new opportunities for creating targeted therapeutics. The study published today in Cell Reports.
Following Roux-en-Y gastric bypass (RYGB), a type of bariatric surgery, many patients exhibit a reduction in taste preference for sweet and fatty foods, although this effect may only be temporary, according to new research from Binghamton University, State University at New York.
The use of probiotics is linked to reduced need for antibiotic treatment in infants and children, according to a review of studies that probed the benefits of probiotics, co-led by a Georgetown investigator.
As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function. That's one explanation for why memory fades and other brain functions decline during old age. But, according to a new study from the University of Illinois, there may be a remedy to delay the inevitable: dietary fiber.
Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2's critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH -- and possibly even reverse early symptoms.
New research suggests that probiotics might not be as effective as we think. Through a series of experiments looking inside the human gut, researchers show that many people's digestive tracts prevent standard probiotics from successfully colonizing them. Furthermore, taking probiotics to counterbalance antibiotics could delay the return of normal gut bacteria and gut gene expression to their naïve state. The research publishes as two back-to-back papers on Sept. 6 in the journal Cell.
A genome wide association study reveals potential genes behind the common painful intestinal condition diverticulitis, and could point the way toward new treatment options.