A study published in the journal Molecular Therapy by Christian Mueller, PhD, shows that using nuclease-free gene editing to correct cells with the mutation that causes alpha-1 antitrypsin deficiency leads to repopulation of a diseased liver with healthy cells. It has the potential to prevent liver and lung damage from forming in very young alpha-1 patients.
National medical organizations jointly issue new recommendations regarding Hepatitis C in pregnancy.
Massachusetts General Hospital investigators have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with the hepatitis C virus who develop chronic infection from those whose immune systems successfully clear the virus.
Researchers have reported a method for successfully removing the cellular material from whole human livers while retaining the organ's three-dimensional structure and extracellular matrix (ECM) components.
Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that these medications alter gut bacteria in a way that promotes three types of chronic liver disease. The study is published Oct. 10 in Nature Communications.
An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.
The opioid epidemic has created a tragic surge in donor organs. But despite their safety record, hundreds of the organs, labeled as 'increased risk,' go unused.
A new article published by JAMA Oncology reports the results of the Global Burden of Disease 2015 study on primary liver cancer incidence, death and years of healthy life lost in 195 countries or territories from 1990 to 2015.
Mice on a fatty diet who were given high levels of fructose in their diet suffered much worse metabolic effects than those given similar calories of glucose.
Healthy people who consume high levels of sugar are at an increased risk of developing cardiovascular disease.