Researchers from NUS Yong Loo Lin School of Medicine's Infectious Diseases Translational Research Programme have discovered that the use of a common antibiotic, doxycycline, in combination with TB drug treatment, reduces the size of lung cavities and accelerates markers of lung recovery. This was done in a trial with 30 pulmonary tberculosis patients.
A comprehensive health-screening program in rural northern KwaZulu-Natal, South Africa, has found a high burden of undiagnosed or poorly controlled non-communicable diseases, according to a study published in The Lancet Global Health.
What The Study Did: Researchers describe the local transmission pattern of SARS-CoV-2 in Valencia, the third most populated city in Spain.
What The Study Did: Researchers reviewed access to COVID-19 vaccination sites in Brooklyn, the most populated borough in New York, to better understand disparities in vaccination.
Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19. By mimicking the receptor that the virus binds to rather than targeting the virus itself, nanodecoy therapy could remain effective against emerging variants of the virus.
What The Study Did: This study examined whether mandatory daily employee symptom data collection can be used as an early alert surveillance system to estimate COVID-19 hospitalizations in communities where employees live.
New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.
What The Study Did: Researchers evaluated the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic (blood) cancers and COVID-19.
What The Study Did: The findings of this study suggest that the increased mortality among Black patients hospitalized with COVID-19 is associated with the hospitals at which Black patients disproportionately received care.
Inhibiting necroptosis, a form of cell death, could yield a new treatment approach for chronic obstructive pulmonary disease (COPD), an inflammatory lung condition also known as emphysema, new research shows. The study, by a team of Australian and Belgian researchers, revealed elevated levels of necroptosis in patients with COPD. By inhibiting necroptosis activity in the lung tissue of COPD patients the researchers found a significant reduction in chronic airway inflammation and lung damage.