Researchers at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression ultimately could help predict disease severity and treatment response, and lead to therapies tailored to each patient's precise biology.
Patients hospitalized for either asthma or chronic obstructive pulmonary disease (COPD) have a higher risk of being readmitted for a hospital stay within 30 days of release if they also suffer from chronic rhinitis, according to a trio of researchers at the University of Cincinnati.
NICE makes a 'strong' recommendation that patients with severe COPD be referred for evaluation for bronchoscopic lung volume reduction, including the Zephyr® Endobronchial Valve System. NICE has broadened the criteria for evaluation and a new group of people for whom lung volume reduction surgery was unsuitable may now be evaluated for treatment with Zephyr Valves, a less invasive treatment option.
Researchers at the Colorado School of Public Health have found a possible connection between the intensity of oil and gas exploration in an area and early indicators of cardiovascular disease among nearby residents.
In a new study, researchers from The Dartmouth Institute for Health Policy and Clinical Practice and the White River Junction VA Medical Center in White River Junction, Vermont, used the most current publicly available data to compare health outcomes for VA and non-VA hospitals within 121 local healthcare markets that included both a VA medical center and a non-VA hospital.
Researchers have demonstrated that influenza virus impairs the immune response to pneumococcus, especially monocyte activity. A software tool developed with FAPESP's support was used to interpret the data.
Researchers predict that death rates from cancer will fall in 2018 in Australasian countries and in Russia. However, a greater proportion of the population will die in Russia from the disease than in any of the other countries, mainly because of the large numbers of men who still smoke. The study is published in Annals of Oncology.
Vitamin C may reduce the harm done to lungs in infants born to mothers who smoke during their pregnancy, according to a randomized, controlled trial published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
Regenerative Medicine is delighted to publish open access original research demonstrating the first virus- and oncogene-free induced pluripotent stem cell (iPSC) technology to produce safer pluripotent stem cells from cord blood and peripheral blood.
Using a mouse model of influenza and experiments that included parabiosis, researchers definitively showed that lung-resident memory B cells establish themselves in the lung soon after influenza infection. Those lung memory B cells responded more quickly to produce antibodies against influenza after a second infection, as compared to the response by the circulating memory B cells in lymphoid tissue, and establishment of the lung-resident memory B cells required a local antigen encounter in the lung.