Researchers at the University of Texas Medical Branch have found SARS-CoV-2 in the testes of infected hamsters. The authors think this may represent what could occur in men with mild to moderate COVID-19 disease.
Researchers from Tokyo Medical and Dental University (TMDU) have found that the urinary secretion of uromodulin, a kidney-specific protein, can be increased by the hormone vasopressin via certain signaling pathways. Increasing the urinary secretion of uromodulin may protect against urinary tract infections and kidney stones, while the resulting lower uromodulin levels in kidney cells may help to prevent hypertension and chronic kidney disease.
USC researchers have created what could be a key building block for assembling a synthetic kidney. In a new study, Zhongwei Li and his colleagues describe how they generate rudimentary kidney structures, known as organoids, that resemble the collecting duct system that helps maintain the body's fluid and pH balance by concentrating and transporting urine. The organoids provide a way to study kidney disease that could lead to new treatments and regenerative approaches for patients.
In the first study to validate conflicting theories, a University of Houston researcher has confirmed that the zinc actually does inhibit and promote the growth of kidney stones at the same time.
In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors. Now, ITQB NOVA researchers led by Maria Miragaia showed evidence that Staphylococcus saprophyticus can originate in food, namely in the meat-production chain.
Kyushu University researchers find that one of the causes of CKD induced heart failures is the over expression of G protein-coupled receptor 68 in monocytes. Monocyte disruption was caused by the activation of the Clock gene, the key regulator of circadian rhythm via the increased level of vitamin A in the body resulting from kidney dysfunction.
A phase 3 clinical trial co-led by Mount Sinai researchers is the first to show that immunotherapy after surgery to remove bladder cancer can reduce the risk of relapse for patients who are at high risk of their cancer returning in a deadly metastatic form, according to results published in The New England Journal of Medicine. The immunotherapy nivolumab was used as an adjuvant therapy, which is given after surgery in the hopes of maximizing its effectiveness.
Smoking in early puberty in boys may have negative consequences for their future generations of offspring, a study from the University of Bergen (UiB) shows.
A new type of penile traction therapy (PTT) device can increase penile length and preserve erectile function in men who have undergone prostate cancer surgery (prostatectomy), reports a clinical trial in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Advanced microscope technology and cutting-edge geological science are giving new perspectives to an old medical mystery: How do kidney stones form, why are some people more susceptible to them and can they be prevented?