Research published in JAMA Internal Medicine found that tamsulosin does not significantly effect patient-reported passage or capture of kidney stones.
An international research team including USC scientists found telltale genetic markers that can be used to predict those most at risk of prostate cancer, a disease common for older men.
The research identifies a new structure in human sperm that functions in the zygote and may provide new avenues for addressing male infertility and insights into early embryo developmental defects.
Perfectly punctual or fashionably late, it takes all kinds to build a kidney. So it is for stem cells as USC scientists building kidney tissue discovered timing is critical as the precise arrival of progenitor cells dictates their form and function in the kidney. The finding will help fabricate kidney components for use in drug tests and treatment of renal disease.
Researchers from Bochum have detected an olfactory receptor in the human bladder that might prove useful for bladder cancer therapy and diagnosis. Using cell culture studies, the team headed by Professor Dr. Hanns Hatt and Dr. Lea Weber demonstrated that the receptor occurs more frequently in bladder cancer tissue than in healthy bladder tissue. Accordingly, significant higher amounts of the receptor could be found in the urine samples of patients.
An operation that targets the nerves connected to the kidney has been found to significantly reduce blood pressure in patients with hypertension, according to a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust.
A robotic system has been developed to automate the production of human mini-organs derived from stem cells. The ability to rapidly, mass produce organoids promises to expand the use of mini-organs in basic research and drug discovery. The system was tested in producing kidney organoids, including models of polycystic kidney disease. The robots were also programmed to analyze the organoids they produced.
Ibuprofen, given instead of antibiotics to women with uncomplicated urinary tract infection (cystitis), leads to longer duration of symptoms and more serious adverse events related to the spread of the primary infection, according to a new study in PLOS Medicine by Ingvild Vik and colleagues from the University of Oslo, Norway.
Pediatric researchers have found that children and adults treated with some oral antibiotics have a significantly higher risk of developing kidney stones. This is the first time that these medicines have been linked to this condition. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics.
The urine of kidney disease patients contains a diverse mix of bacteria such as Staphylococcus and Streptococcus, according to a Loyola study. The bacteria diversity generally was higher among kidney patients who also experienced urinary urgency (sudden, urgent need to urinate). The findings could lead to new approaches to treating lower urinary tract problems such as urinary urgency and incontinence.