A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.
A research team led by Prof. ZHENG Hairong from the Shenzhen Institutes of Advanced Technology developed a "dual-step iterative temperature estimation (DITE)" method for fat-referenced PRFS temperature imaging in fat-containing tissues. By modulating BAT activity, this study provides crucial insight relevant to the treatment of metabolic diseases such as diabetes, obesity, and non-alcoholic fatty liver disease.
A new review by the International Osteoporosis Foundation Working Group on Cancer and Bone Disease looks at the major factors affecting bone health in mematologic stem cell transplant recipients, and provides expert guidance for the monitoring, evaluation and treatment of bone loss in these patients.
Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes, both of which are risk factors for cardiovascular disease and other serious conditions.
Type 2 diabetes has been linked with an increased risk of cognitive dysfunction and dementia, but the underlying mechanisms are uncertain. In a new Diabetic Medicine study, imaging tests revealed that changes in white matter regions of the brain that are indicative of small vessel disease are associated with decreased processing speed (the the time it takes a person to do a mental task) in people with Type 2 diabetes.
Vitamin D is already well known for its benefits in building healthy bones. A new study supports the idea that it also may reduce cancer risk as well as breast cancer mortality, especially in women with a lower body mass index. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
New research from University of Sydney has found home-based video-game exercises can reduce chronic low back pain in older people by 27 percent, which is comparable to benefits gained under programs supervised by a physiotherapist.
Scientists continue to unravel links between body weight and the gut microbiome. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) report an unexpected finding: mice fed a fatty diet and mannose, a sugar, were protected from weight gain -- and this effect tracked with changes in the gut microbiome. The study published today in Cell Reports.
Noticing that songbirds never seem to get fat despite overeating at bird feeders, London environmental biologist Lewis Halsey wondered whether the amount of energy birds put into singing, fidgeting, or exercising could be adjusted in ways that regulate weight. In a literature review published Sept. 18 in the journal Trends in Ecology & Evolution, he explores whether songbirds don't need to worry about their calorie counts because they can control the way their bodies use energy.
The new system did not minimize pre-transplant dialysis exposure for patients who were not waitlisted preemptively.