Diabetes is associated with various health problems including decline in skeletal muscle mass. A Japanese research group revealed that elevation of blood sugar levels leads to muscle atrophy and that two proteins play key roles in this phenomenon. These findings were published on Feb. 21 in the online edition of JCI Insight.
A new study led by Salk Institute scientists suggests that high-fat diets fuel colorectal cancer growth by upsetting the balance of bile acids in the intestine and triggering a hormonal signal that lets potentially cancerous cells thrive. The findings, which appeared in Cell on Feb. 21, 2019, could explain why colorectal cancer, which can take decades to develop, is being seen in younger people growing up at a time when higher-fat diets are common.
Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to biliary atresia (BA), the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children.
There is not enough evidence related to the effects of noncaloric sweeteners on appetite, short-term intake, and risk of suffering from cancer or diabetes, according to the conclusions of this review.
People with diabetes have a 35 percent higher risk of experiencing low back pain and 24 percent higher risk of having neck pain than those without diabetes, a review by University of Sydney researchers has found.
A new study gives insight into the complexity of genetic and environmental factors that compel some of us to drink and smoke more than others.
A UC San Francisco study of human and mouse pancreatic tissue suggests a new origin story for type 1 (T1) diabetes. The findings flip current assumptions about the causes of the disease on their head and demonstrate a promising new preventative strategy that dramatically reduced disease risk in laboratory animals.
A pair of Affordable Care Act clauses had a sizable effect on the ability of people with diabetes to get health insurance, a new study suggests. Before the requirements took effect, the percentage of people with private health insurance who had diabetes had declined, but it began to increase again after the ACA required insurers to accept people with pre-existing conditions, and limited their ability to charge higher rates to older people.
The smell of food affects physiology and aging. That is the result of research conducted on the model organism of the roundworm by a research team led by Professor Thorsten Hoppe at the Cluster of Excellence for Aging Research (CECAD). Surprisingly, this relationship is due to a single pair of olfactory neurons. The results have now been published in Nature Metabolism.
Hypertension is an important public health problem that can lead to life-threatening cardiovascular events, including heart attack and stroke. Here, the relationship between dietary intake of n-6 fatty acids and hypertension, using blood pressure measurement and a diet history questionnaire. A Kanazawa University research team found that increased dietary intake of n-6 fatty acids positively impacted hypertension, but that this benefit was limited to individuals without impaired glucose tolerance.