Insulin in the brain may help regulate the hunger sensation and improve functional connectivity in certain cognitive brain regions (default-mode network, DMN *) as well as in the hippocampus and hypothalamus. This is the finding of a new study by researchers at the German Center for Diabetes Research (DZD) in Tübingen.
Peroxisomal biogenesis disorder, which has been linked only to lipid metabolism, is also associated with sugar metabolism.
Some insulin is still produced in almost half of the patients that have had type 1 diabetes for more than ten years. Patients with remaining insulin production had much higher levels in blood of interleukin-35, They also had much more immune cells that produce interleukin-35 and dampen immune attacks.
Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen. In comparison to electron microscopes, the device can visualize transparent biological structures without introducing contrast agents. The paper was published in Applied Physics Letters.
Type 2 diabetes (T2D) and osteoporosis often coexist in patients, but managing both conditions can be a challenge. A comprehensive review published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism highlights the most effective treatment options for treating these conditions together.
Results from four recent randomized clinical trials suggest that using medications that offer glucose control while reducing the risk for cardiovascular disease could improve patient outcomes.
Monitoring and maintaining glucose levels of critically ill patients after admission from ICU, to general care through their discharge from the hospital may have positive impact on outcomes.
Infections during infancy are associated with increased risk for gluten intolerance (celiac disease) later on. Apparently the risk is particularly high in the case of repeated gastrointestinal infections in the first year of life. This conclusion was drawn by scientists of the Institute for Diabetes Research at Helmholtz Zentrum München after analyzing data provided by the Bavarian Association of Statutory Health Insurance Physicians. The study has now been published in the American Journal of Epidemiology.
Combustion is often a rapid process, like fire. How can our cells control the burning process so well? The question has long puzzled researchers. Using bacteria from hot springs, researchers from Stockholm University now have the answer.
A vaccine to immunise people against high levels of cholesterol and the narrowing of the arteries caused by build-up of fatty material (atherosclerosis) may be possible following successful results in mice. Now, a phase I trial in patients has started to see if the findings translate to humans. The study is published in the European Heart Journal.