New study finds that integrating two separate clinical risk score models more accurately assesses the stroke risk of patients with Afib.
Atrial fibrillation patients who are diagnosed with carotid artery disease face higher risks for developing dementia, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.
Researchers at Albert Einstein College of Medicine and Shanghai Jiao Tong University School of Medicine in China have identified an enzyme that helps cancer cells make the building materials they need to quickly proliferate. Inhibiting this enzyme could be a strategy to slow down cancer growth, leading to more effective treatments. The study was published in the April 27 issue of the Journal of Biological Chemistry.
Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer. According to a new study from the University of Illinois, the way walnuts impact the gut microbiome -- the collection of trillions of microbes or bacteria in the gastrointestinal tract -- may be behind some of those health benefits.
Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment. This marks the first time researchers have delivered CRISPR/Cas9 repressors for targeted therapeutic gene silencing in adult animal models.
Analysis of high-resolution genomic data in a large study population reveals novel low-frequency polymorphisms that drive response to dietary lipids and medication.
Eating fatty fish increases the size and lipid composition of HDL particles in people with impaired glucose metabolism, according to a new study from the University of Eastern Finland. These changes in the size and lipid composition of HDL particles make them beneficial for cardiovascular health. Published in Molecular Nutrition & Food Research, the study also found that camelina sativa oil decreases the number of harmful IDL particles.
Cholesterol-lowering drugs are more likely to save thousands of additional lives when used in people with higher levels of LDL cholesterol, or 'bad' cholesterol, according to a new study from the University of Iowa, published in the Journal of the American Medical Association (JAMA).
A new paper published in Circulation by researchers at La Jolla Institute for Allergy and Immunology reports successful vaccination of atherosclerotic mice with a small chunk of protein snipped out of 'bad cholesterol.' Vaccination reduced plaque levels in test mice, and other experiments with human blood samples identified the class of T cells likely responsible for positive outcomes. The paper suggests that a comparable strategy could form the basis of a human vaccine.
The so-called good cholesterol, HDL, is associated with infectious disease, new research from the University of Copenhagen and Copenhagen University Hospital shows.