A new animal study shows how insulin controls the movement and storage of fat molecules in the liver and how a breakdown in this system could lead to non-alcoholic fatty liver disease and changes in circulating lipid levels associated with cardiovascular disease.
High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found that the culprit is a byproduct of cholesterol metabolism that acts on specific immune cells so that they facilitate the cancer's spread instead of stopping it.
Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have identified a protein that holds promise as a target for therapies to reduce obesity. Drs. Guadalupe Sabio and Nuria Matesanz have demonstrated that MKK6 controls the conversion of fat stores, known as white fat, into brown fat, in which lipids are burned to maintain body temperature and reduce obesity.
Despite prevention efforts, researchers have found a significant increase over a 10-year period in the percentage of people with stroke who have high blood pressure, diabetes, smoking and other risk factors for stroke. The study is published in the Oct. 11, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at the University of California, Riverside have tested a genetically modified soybean oil used in restaurants and found that while it induces less obesity and insulin resistance than conventional soybean oil, its effects on diabetes and fatty liver are similar to those of conventional soybean oil, the major vegetable cooking oil used in the United States, with popularity on the increase worldwide. The study also compares the GM soybean oil to coconut and olive oils.
Skipping breakfast is associated with an increased risk of atherosclerosis, or the hardening and narrowing of arteries due to a build-up of plaque, according to research published today in the Journal of the American College of Cardiology.
In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene.
New research links the equipping of mobile fruit and vegetable stands with wireless banking devices programmed to accept food stamps to the buying of more healthy foods by people with low incomes.
The engine used by cancer-killing 'Natural Killer' cells is turned on by a protein called Srebp, which can be blocked by certain sterols like cholesterol. Tumor cells can produce oxysterols and cholesterol levels tend to be higher in people with obesity.
Research from Aarhus University sheds new light on how the body converts the bad kind of cholesterol. The discovery could lead to new and potentially more effective medicine.