Nearly four out of five diabetic patients with severe cases of a disabling condition called Charcot foot were able to walk normally again following surgery, a Loyola Medicine study has found.
A centralized chronic disease management program produced significant improvements in the care of patients with diabetes, hypertension or cardiovascular disease treated at practices in the Massachusetts General Hospital primary care network.
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered how high glucose levels -- whether caused by diabetes or other factors -- keep heart cells from maturing normally. Their findings help explain why babies born to women with diabetes are more likely to develop congenital heart disease.
Risk factors for developing cardiovascular disease or eye and renal damage following type 2 diabetes are much more common among patients who are diagnosed before the age of 45 than in elderly newly-diagnosed patients. According to researchers behind a study from Aarhus University, this is a situation that the healthcare sector should take seriously and adapt to.
A computing system with artificial intelligence that can learn to do tasks that normally require human intelligence could detect retinal images that did and did not show diabetic retinopathy and related eye diseases in multiethnic populations.
Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes. 'We see that people with known risk factors such as high blood sugar and high blood fats also have heightened death receptor levels,' says Professor Jan Nilsson who led the study.
'We decided to create new approaches to prevention and treatment of diabetes by using synthesized anti-diabetic chemical compounds. It was important for us to understand the mode of their action on cell, tissue, organ, and body levels,' said Irina Danilova, the author of the research.
Diabetes is known to increase a person's risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunction increases the risk of diabetes. Further, the researchers deduced that a likely culprit of the two-way relationship between kidney disease and diabetes is urea. The findings are significant because urea levels can be lowered through medication and diet.
An individualized approach to glucose control in type 2 diabetes can save billions of dollars over time nationwide due to decreased medication costs and would slightly improve quality of life compared with uniform intensive control (HbA1C level < 7 percent).
A cost analysis by researchers at the University of Chicago Medicine shows treatment plans that set individualized blood sugar goals for diabetes patients, tailored to their age and health history, can save $13,546 in health care costs over their average lifetime when compared with treatment strategies that stick to a uniform national standard.