Studies have found an association between insufficient sleep and the development of insulin resistance, one of the factors that cause type 2 diabetes, and now researchers have discovered a biological reason for this relationship, at least in men: an imbalance between their testosterone and cortisol hormones. The study results will be presented Sunday at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Ill.
Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy -- a rare but fatal form of muscular dystrophy -- were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease.
The ability to generate spoken verbs in infinitive in a given time begins to worsen in the early stages of Alzheimer's disease (AD). Thus, the verb fluency test has been found to be a suitable neuropsychological tool for the detection of healthy aging people at risk of developing cognitive impairment, according to a recent research of the Research Center and Memory Clinic. Fundació ACE. Institut Català de Neurociències Aplicades, UIC-Barcelona, Spain.
The achievements of three girls who received intensive therapy through the Virginia Tech Carilion Research Institute's Neuromotor Research Clinic based on innovative pediatric neurorehabilitation research have been documented in a report published in BMC Research Notes.
A research conducted by the UAB demonstrates that mice suffering from this disease also have substantial malfunctions in small blood vessels, important in nourishing different organs and tissues and in regulating blood pressure, and which mainly affects females. The study also demonstrates a correlation between the state of peripheral blood vessels and different levels of anxious behaviour, both in normal ageing and in those suffering from Alzheimer's disease.
A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer's disease (AD)-related amyloid-β peptide (Aβ) under near-infrared (NIR) light irradiation is developed. The catalyst was able to oxygenate Aβ embedded under the skin of a living mouse, and diminished intact Aβ level in AD-model mouse brain. The new catalyst is potentially applicable for the treatment of peripheral amyloid diseases and AD.
Researchers from UNSW Sydney and the Black Dog Institute have questioned the efficacy and safety of intranasal ketamine for depression, with their pilot trial stopped early due to poor side effects in patients.
In a paper published online March 5 in Nature Communications, University of Washington researchers unveiled an open-access browser to display, analyze and share neurological data collected through a type of magnetic resonance imaging study known as diffusion-weighted MRI.
While there has been an increased focus on person-centered models of care transition for cognitively intact older adults from hospital to home, little is known about the core elements of successful transitions in care specifically for persons with dementia.
Neuroscientists at the Sainsbury Wellcome Centre have identified a circuit in the primary visual cortex (V1) of the brain that integrates head- and visual-motion signals. The study, published today in Neuron, elucidates the mechanisms by which visual and vestibular inputs to the brain sum together to enable appropriate behavioural responses.