Like swinging a tennis racket during a ball toss to serve an ace, slow and speedy brainwaves during deep sleep must sync up at exactly the right moment to hit the save button on new memories, according to new UC Berkeley research.
An international team of scientists have confirmed the discovery of a major cause of dementia, with important implications for possible treatment and diagnosis.
Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer's, Parkinson's, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered which of these subtypes are most susceptible to common risk factors for different brain diseases.
Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study in Scientific Reports by Lewis Katz School of Medicine at Temple University researchers associates canola oil consumption in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer's disease. It's the first study to suggest that canola oil is more harmful than healthful for the brain.
About 15 million Americans will have either Alzheimer's dementia or mild cognitive impairment by 2060, up from approximately 6.08 million this year. The findings highlight the need to develop preventive measures that could slow the progression of the disease in at risk for Alzheimer's dementia.
Researchers have found a two-way link between traumatic brain injury and intestinal changes. These interactions may contribute to increased infections in these patients, and may also worsen chronic brain damage.
A drug already used to treat certain forms of cancer appears to be an effective therapy for Huntington's disease, and offers a potential pathway to treat other neurodegenerative diseases.
Houston Methodist is making mini brains from human stem cells, putting researchers on a fast track to repair the nervous system after injury or disease of the brain and spinal cord. Researchers have developed a new system to reduce the time it takes to grow these brain models, which will give them the ability to screen drugs and study what's behind disease-causing mutations more quickly. The findings appear Dec. 12 in Stem Cell Reports.
Playing 3-D platform video games on a regular basis may improve cognitive functions in seniors and increase grey matter in a brain structure called the hippocampus, an Université de Montréal study suggests.
In the December featured basic science article in The Journal of Nuclear Medicine, Belgian researchers report on the first large-scale longitudinal imaging study to evaluate BACE1 inhibition with micro-PET in mouse models of Alzheimer's disease. PET imaging has been established as an excellent identifier of the amyloid plaque and tau tangles that characterize Alzheimer's disease. Now it is proving to be an effective way to gauge treatment effectiveness.