University of Saskatchewan (USask) researchers have used a novel combination of techniques to compare the effects of two families of pesticides used in agriculture, and found that at low dosages the newer pesticide is less toxic than a currently used neonicotinoid one.
Why do some people almost always drop $10 in the Salvation Army bucket and others routinely walk by? One answer may be found in an intricate and rhythmic neuronal dance between two specific brain regions, finds a new Yale University study published Feb. 24, 2020 in the journal Nature Neuroscience.
Brains of young men with autism spectrum disorder (ASD) have low levels of a protein that appears to play a role in inflammation and metabolism.
Although 1 in 7 adults smoke cigarettes the year prior to undergoing weight-loss surgery, nearly all successfully quit at least a month before their operation. However, smoking prevalence steadily climbs to pre-surgery levels within seven years, according to new research. The findings suggest that there may be missed opportunities to engage patients in interventions to improve long-term smoking cessation rates, particularly at regular post-surgery checkups.
Brazilian researchers working in collaboration with Canadian scientists demonstrated that all medulloblastoma tumor subtypes express two stem cell markers: BMI1 and CD133. When they induced DNA chromatin relaxation, tumor cell viability was reduced with down-regulation of BMI1 and CD133. These anti-tumor effects could be potentiated by concurrent inhibition of MAPK/ERK signaling.
A cutting-edge MRI technique to detect iron deposits in different brain regions can track declines in thinking, memory and movement in people with Parkinson's disease, finds a new UCL-led study published in the Journal of Neurology, Neurosurgery, and Psychiatry.
Researchers explain symptoms associated with Antidepressant Discontinuation Syndrome and provide a schedule for tapering various classes of antidepressants. Patients who stop medication without tapering often experience flulike symptoms, insomnia, nausea, imbalance, sensory disturbances often described as electric shocks or 'brain zaps', and hyperarousal.
A naturally occurring amino acid is gaining attention as a possible treatment for ALS following a new study published in the Journal of Neuropathology & Experimental Neurology. It showed the amino acid, L-serine, successfully reduced ALS-like changes in an animal model of ALS. After exposure to the cyanobacterial neurotoxin, BMAA, vervets developed pathology similar to the earliest stages of ALS in humans. However, vervets that also received the amino acid L-serine had significantly reduced ALS pathology.
A sweeping new set of findings by Salk researchers reveals previously unknown details explaining why some neurons in bipolar patients swing between being overly or under excited. The researchers used experimental and computational techniques to describe how variations in potassium and sodium currents in the brain cells of people with bipolar disorder may help to further explain why some patients respond to lithium and others do not.
Genetic mechanisms that govern brain plasticity -- the brain's ability to change and adapt -- have been uncovered by researchers at the University of Birmingham.