A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer's disease (AD)-related amyloid-β peptide (Aβ) under near-infrared (NIR) light irradiation is developed. The catalyst was able to oxygenate Aβ embedded under the skin of a living mouse, and diminished intact Aβ level in AD-model mouse brain. The new catalyst is potentially applicable for the treatment of peripheral amyloid diseases and AD.
In a paper published online March 5 in Nature Communications, University of Washington researchers unveiled an open-access browser to display, analyze and share neurological data collected through a type of magnetic resonance imaging study known as diffusion-weighted MRI.
Neuroscientists at the Sainsbury Wellcome Centre have identified a circuit in the primary visual cortex (V1) of the brain that integrates head- and visual-motion signals. The study, published today in Neuron, elucidates the mechanisms by which visual and vestibular inputs to the brain sum together to enable appropriate behavioural responses.
New research led by Plymouth University Peninsula Schools of Medicine and Dentistry shows how the drug QNZ-46 can help to lessen the effects of excess release of glutamate in the brain -- the main cause of brain injury in stroke. As stroke is the second leading cause of disability and early death in the UK, this study could offer hope to thousands of people at risk.
A new study reveals that preverbal infants are able to make rational deductions, showing surprise when an outcome does not occur as expected.
University of Houston researchers link autism spectrum disorders to defects in a nuclear receptor inside the brain. And just like that, this world-renowned team advances the understanding of autism.
Treatments for the anti-NMDA receptor encephalitis usually include steroids, intravenous immunoglobulin, plasma exchange, plasmapheresis, rituximab, cyclophosphamide and tumor resection. The researchers aimed to compare the efficacy of the treatments including intravenous immunoglobulin, plasma exchange, plasmapheresis, rituximab or cyclophosphamide for male anti-NMDA receptor encephalitis patients without tumor and to discuss potential biomarkers for this disease.
'Has this patient been drinking?' It's a critical question for neurosurgical nurses and other professionals when evaluating patients with traumatic brain injury (TBI). But some groups of TBI patients are less likely to be screened for alcohol use, including women and younger patients, reports a study in the March issue of the Journal of Neuroscience Nursing, official journal of the American Association of Neuroscience Nurses.
An interdisciplinary group of physicists and biologists working on research into brain cells have come up with a new, revolutionary microscopy technique which for the first time allows images to be obtained of all the cells within a specified area of living brain tissue.
A study led by researchers at Tokyo Institute of Technology (Tokyo Tech) has uncovered new ways of driving multi-legged robots by means of a two-level controller. The proposed controller uses a network of so-called non-linear oscillators that enables the generation of diverse gaits and postures, which are specified by only a few high-level parameters. The study inspires new research into how multi-legged robots can be controlled, including in the future using brain-computer interfaces.