A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge.
Adjusting the frequency and dosage of Parkinson's patients' medication is complex. In their 'ON' state they respond positively to medication and in their 'OFF' state symptoms return. Addressing these fluctuations requires a clinical exam, history-taking or a patient's self-report, which are not always practical or reliable. A new technology that combines an algorithm with a senor-based system using wearable motion sensors, automatically, continuously and reliably detects a patient's medication ON and OFF states without patient or physician engagement.
Less than one hour of brain training with neurofeedback leads to a strengthening of neural connections and communication among brain areas. This is the main finding of a new study conducted at D'Or Institute for Research and Education (IDOR), published today in Neuroimage. According to the authors, the study may pave the way for the optimization and development of therapeutic approaches against stroke and Parkinson's, for example.
Learning how to tie a shoe or shoot a basketball isn't easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right. Now, Rutgers scientists have discovered that sensory signals in the brain's cerebral cortex, which plays a key role in controlling movement and other functions, have a different pattern of connections between nerve cells and different effects on behavior than motor signals. The motor area of the cortex sends signals to stimulate muscles.
A new material automatically 'listens' to the brain, leading to more sensitive electronics that could detect neurological disease sooner.
Researchers are reporting early success with a new tool to help people with Parkinson's disease improve their balance and potentially decrease falls with high-tech help: virtual reality. After practicing with a virtual reality system for six weeks, people with Parkinson's disease demonstrated improved obstacle negotiation and balance along with more confidence navigating around obstacles in their path.
A new paper published in Nature Reviews Neurology suggests that recent advances in deep brain stimulation (DBS) for Parkinson disease could lead to treatments for conditions such as obsessive-compulsive disorder (OCD), Gilles de la Tourette syndrome and depression. The authors of the paper argue that bi-directional electrodes which can both stimulate and record from deep brain structures -- known as closed-loop DBS -- could have applications beyond Parkinson disease.
Iban Ubarretxena, an Ikerbasque Researcher and Director of the Biofisika Institute (CSIC-UPV/EHU), participates in a piece of research that has enabled new inhibitors to be identified and which could be used to develop drugs to combat Parkinson's. The research has been published in the prestigious journal Cell Research.
A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease. The findings point to a pathway to possible treatments for this disease and better understanding of other neurodegenerative disorders, including Alzheimer's disease, that affect millions.
Parkinson's patients could be helped by fresh insights gained from studies of tiny tropical fish. Research from the University of Edinburgh using zebrafish has revealed how key brain cells that are damaged in people with Parkinson's disease can be regenerated.