An international group of researchers led by Professor Wim Versées (VIB-VUB) has unraveled the workings of an essential mechanism in 'Parkinson's protein' LRRK2. Their study demonstrates a direct link between the protein's 'dimerization' -- two copies that are bound together -and mutations that lead to Parkinson's disease. This process could eventually lead to a promising therapy route.
Health professionals can deliver quality neurological care remotely to patients through the emerging field of teleneurology. However, medical training has not caught up with the field, and a lack of formalized education for teleneurology doesn't exist. Now, a researcher at the University of Missouri School of Medicine, as part of an American Academy of Neurology (AAN) team, has developed a standardized curriculum for providing remote neurology care via telecommunication.
A new study in Cell Reports by Matthew Wanat, assistant professor of biology at The University of Texas at San Antonio (UTSA), sheds light on how dopamine cells in the brain signal the passage of time.
Globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy etc) has increased substantially over the past 25 years. This problem is the topic of a recent report by the Global Burden of Disease (GBD) international project, which was published in The Lancet. One of its participants is Vasily Vlassov, Professor at the Faculty of Social Sciences, the Higher School of Economics.
Using a modified version of the CRISPR genome editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases. They used this system to turn on randomly chosen genes in many different cells, allowing them to identify genes that protect cells from a protein associated with Parkinson's disease.
Problems with olfaction have been linked to a variety of health conditions. Scientists have developed new tests to detect smell loss more reliably.
Scientists at the University of Dundee have identified the structure of a key enzyme that protects the brain against Parkinson's disease. The result of a decade of work, the research team said that solving the 3-D structure and inner workings of the PINK1 enzyme represented a major breakthrough.
Researchers at The Scripps Research Institute (TSRI) may have found a way to help doctors diagnose diseases like Alzheimer's and Parkinson's earlier in their progression.
Scientists discover the anatomical link for the loss of smell in Parkinson's disease.
Research shows the Parkinson's disease drug carbidopa displays significant anticancer effects in both human cell lines and mice when given at normal patient dosage levels.