Pingpong may hold promise as a possible form of physical therapy for Parkinson's disease. People with Parkinson's who participated in a pingpong exercise program once a week for six months showed improvement in their Parkinson's symptoms, according to a preliminary study released today that will be presented at the American Academy of Neurology's 72nd Annual Meeting in Toronto, Canada, April 25 to May 1, 2020.
Several processes in the roundworm C. elegans boost the stress response in cells, incidentally making worms resistant to a high-fat diet and extending their lifespan. UC Berkeley researchers have found another: cells called glia that release a hormone that boosts the unfolded protein response in the endoplasmic reticulum of the worm's cells, effectively doubling lifespan. This could lead to interventions to tune up peripheral cells, such as muscle cells, and prevent age-related deterioration in humans.
A cutting-edge MRI technique to detect iron deposits in different brain regions can track declines in thinking, memory and movement in people with Parkinson's disease, finds a new UCL-led study published in the Journal of Neurology, Neurosurgery, and Psychiatry.
As out-of-pocket costs go up for drugs for the neurologic disorders Alzheimer's disease, peripheral neuropathy and Parkinson's disease, people are less likely to take the drugs as often as their doctors prescribed, according to a study funded by the American Academy of Neurology and published in the Feb. 19, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The top contributor to familial Parkinson's disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies.
A promising molecule has offered hope for a new treatment that could stop or slow Parkinson's, something no treatment can currently do.
Astrocytes are neural cells with many important functions in the nervous system. The inflammation of these cells occurs in brain infections and neurodegenerative disorders, a process called astrogliosis. Aware of this fundamental process for the prevention of diseases and improvement of current treatments, a team led by researchers at the D'Or Institute for Research and Education (IDOR) and other five Brazilian Federal Universities published one of the first studies to categorically observe this inflammatory reaction in human astrocytes created in the laboratory.
Parkinson's disease is a long-term (chronic) neurological condition that affects the way the brain co-ordinates body movements like walking and talking, as well as cognitive abilities. There is currently no cure for the disease, but researchers at Trinity have recently published findings of a study which may lead to better treatments for this debilitating illness. The paper has been published in the international Cell Press journal Structure.
Disease-prompting bundles of proteins found within cells are cleared by unexpected processes. That knowledge could lead to ALS therapeutic solutions.
In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.