Subconcussive head impacts from sports are those that don't cause symptoms of a concussion. This randomized clinical trial evaluated whether such subconcussive head impacts from soccer-ball headings impaired brain circuitry linking eye and cognitive functions in adult soccer players compared with a control group of players that only kicked the soccer ball.
Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in the New England Journal of Medicine.
Visual acuity--the ability to discern letters, numbers, and objects from a distance--is essential for tasks including recognizing a friend across a room and driving. Researchers previously assumed visual acuity was primarily determined by the eye's optics and the retina's anatomy. University of Rochester researchers show that small eye movements humans aren't even aware of making also play a large role in visual acuity. The research may lead to improved treatments for vision impairments.
Researchers have identified a new protein linked to age-related macular degeneration (AMD) that could offer new hope for the diagnosis and treatment of the disease, which affects over 1.5 million people in the UK alone.
An international team of scientists has identified a protein which is strongly linked to the commonest cause of blindness in developed countries when its levels are raised in the blood.
Visit adherence plays an important role in outcomes for patients with age-related macular degeneration, a Penn Medicine study found.
The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists from the Technical University of Munich (TUM) has now uncovered the precise structure of the alpha-A-crystallin protein and, in the process, discovered an important additional function.
Researchers have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types -- the most commonly used viral vectors for in vivo gene therapy. The researchers identified that GPR108, a G protein-coupled receptor, served as a molecular 'lock' to the cell. The discovery could one day enable scientists to better direct AAV gene transfers to specific tissues.
It would be the first treatment for dry age-related macular degeneration and could significantly improve treatment for wet AMD.
Researchers have identified 107 genes that increase a person's risk of developing the eye disease glaucoma, and now developed a genetic test to detect those at risk of going blind from it. The research, led by QIMR Berghofer Medical Research Institute and Flinders University in Australia, has been published today in the international Nature Genetics journal.