A new review by the International Osteoporosis Foundation Working Group on Cancer and Bone Disease looks at the major factors affecting bone health in mematologic stem cell transplant recipients, and provides expert guidance for the monitoring, evaluation and treatment of bone loss in these patients.
Arthritis is common in individuals with varying degrees of depression, according to a new International Journal of Geriatric Psychiatry study.
Researchers from the University of North Carolina and Brigham Young University conducted a study to observe walking biomechanics of 130 subjects who have had ACL reconstruction surgery. They found people who report lingering symptoms post-surgery either underload their injured leg (6-12 months after surgery) or overload the injured leg (after the 24-month mark), as compared to those who have had the surgery but no longer report symptoms.
With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report.
Pectus excavatum, pectus carinatum, Poland syndrome, sunken chest deformity, barrel chest deformity, body builder deformity, and long upper chest wall are chest wall deformities that are documented in the medical literature.
Medicaid expansion under the Affordable Care Act does not appear to have reduced disparities in the use of regionalized surgical care among vulnerable persons.
An extensive review of 25 randomized clinical trials found 'little evidence' that invasive surgery was more effective than sham or placebo procedures in reducing chronic pain. The study was published in the journal Pain Medicine.
Answers to treating muscular dystrophies could lie in better understanding muscle repair -- which resembles a delicate cellular dance choreographed by special cells called fibro-adipogenic progenitors (FAPs). Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have revealed that FAPs don't have just one identity -- but several distinct identities that emerge during key stages of muscle regeneration. These cells they could be targeted for drug development. The study was published in Nature Communications.
A paper published recently in the scientific journal Nature Reviews Cardiology shows that regular physical exercise and, specifically, that which is undertaken to increase muscle strength, improves cardiovascular health through non-traditional mechanisms, such as, for example, the release through the skeletal muscles of substances that are healthy for the heart (known as myokines) or the improvement in intestinal microbiota (the microorganisms in the intestines).
Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, M.D., Ph.D., collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage. Their findings appear today in Nature Communications.