Early surgery to repair tears of one of the shoulder rotator cuff muscles provides lasting improvement in strength, function, and other outcomes, reports a study in the Aug. 16, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
Existing evidence on the use of gabapentinoids in chronic low back pain (CLBP) is limited, and demonstrates significant risk of adverse effects with no benefits on pain relief, according to a meta-analysis published in PLOS Medicine by Harsha Shanthanna from McMaster University, Canada, and colleagues.
A group of genes involved in calcium handling undergoes a highly-regulated process called alternative splicing that changes the type of protein the genes produce as muscles transition from newborn to adult.
Orthopaedists can help prevent injuries; put people back together; provide patients with in-home exercises and ergonomically proper reconditioning programs; or pair patients with rehabilitation professionals for nonsurgical or post-surgical rehabilitation therapies. According to a new literature review published in the Journal of the American Academy of Orthopaedic Surgeons, therapeutic modalities -- or physical therapy -- can be a useful addition to exercise or to manipulative therapy to help improve bone-and-joint-based function affected by pain and/or injury.
New research indicates that weather conditions in 45 US cities are indeed associated with Google searches about joint pain. But it might not be the association you'd expect. The findings suggest that people's activity level -- increasing as temperatures rise, to a point -- is likelier than the weather itself to spur online searches about knee and hip pain, the investigators say.
In a forthcoming special issue of Tissue Engineering on 'Strategic Directions in Musculoskeletal Tissue Engineering,' Guest Editors Megan Killian, PhD, University of Delaware, MD and Anne Gingery, PhD, Mayo Clinic, MI have compiled a diverse group of scientific articles by leading researchers who are using novel approaches to tissue engineering to develop treatments for musculoskeletal disorders.
Scientists exploring the brain for answers to certain sleep disorders may have been looking in the wrong place.
Unlike other back-saving devices, this one is mechanized and was tested with motion capture, force plates and electromyography.
Duchenne muscular dystrophy is a rapidly progressive disease that causes whole-body muscle weakness and atrophy due to deficiency in a protein called dystrophin. Researchers have developed a new gene transfer approach that uses an adeno-associated virus vector to deliver a modified dystrophin gene to muscle, restoring muscle strength in a mouse model that closely mimics the severe defects seen in patients. The study appears July 27 in Molecular Therapy - Methods & Clinical Development.
A new study led by researchers at University Hospitals Coventry and Warwickshire NHS Trust and the University of Warwick has recommended an alternative method of pain relief for patients undergoing knee replacement surgery.