Skull fractures and other head and facial injuries from motorcycle trauma in Michigan have doubled since that state relaxed its motorcycle helmet laws, reports a study in the June issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). The new study is one of the first to focus on how helmet laws affect CMF trauma rates.
For some patients undergoing intestinal or multi-organ transplantation, closing the abdominal wall poses a difficult surgical challenge. Total abdominal wall transplantation provides an alternative for abdominal closure in these complex cases, according to a state-of-the-art approach presented in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.
A study this month from researchers at the University of Wisconsin-Madison and the University of California, San Francisco (UCSF) shows mindfulness training that addresses fear and pain during childbirth can improve women's childbirth experiences and reduce their depression symptoms during pregnancy and the early postpartum period.
Duke University researchers found that a molecule called PD-L1, which is blocked by the immunotherapy drug nivolumab, acts not only on immune cells but also on the nerve cells that signal pain. That insight could lead to a simple test that measures subtle differences in pain sensitivity to gauge whether or not a cancer patient is responding to immunotherapy. This study also identifies PD-L1 as a previously unrecognized neuromodulator and pain inhibitor.
Vitamin D supplementation combined with good sleeping habits may help manage pain-related diseases. This paper published in the Journal of Endocrinology, reviews published research on the relationship between vitamin D levels, sleep and pain management, and reports that levels of vitamin D combined with good quality sleep could help manage conditions including arthritis, menstrual cramps and chronic back pain.
Modelling of how protein 'switches' are activated, leading to electrical signals in the brain, paves the way for understanding how brain activity can be controlled by existing and new drugs, including anesthetics.
Chronic pain in any one body part may distort the intensity with which a key brain region perceives pain everywhere else.
A team of investigators found patients who had higher pain catastrophising, the degree of an exaggerated, negative response to pain, were more likely to take opioids for pain relief. They found that patients who used opioids to manage their knee pain before their total knee replacement had less pain relief after the operation.
Six months after knee replacement surgery, pain outcomes were not as good for patients who previously took prescription opioids, according to a study in the May 17 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
Women with endometriosis -- a common and painful disease linked to infertility -- have called for more studies to understand its causes and find a possible cure. Their calls are the outcome of a major consultation process -- led by the University of Edinburgh -- that has pinpointed ten priorities for future research into the disease.