Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be used as an approach to developing new antiviral drugs to treat the serious infectious disease, according to a study by the Institute for Biomedical Sciences at Georgia State University published in PLoS Pathogens.
An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer. The study results, published today in Nature Communications, suggest that scientists have identified a unique way to disrupt the cellular process that contributes to Diffuse Intrinsic Pontine Gliomas (DIPG).
An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity. The Early Growth Genetics Consortium discovered a robust new signal, fine-mapped previously reported genetic variants, and added to evidence that genetic influences on obesity operate across the lifespan.
Fires, tornadoes and other natural disasters are outside of the control of care teams. But it is within our team's control to train neonatal intensive care unit staff to master emergency evacuations, a necessary skill, says Lisa Zell, BSN, a clinical educator at Children's National in Washington, D.C.
Cerebral palsy (CP) is one of the most common movement disorders in children. A growing number of caregivers worldwide are caring for children, adolescents and adults with child-onset CP. In this collection of articles in the Journal of Pediatric Rehabilitation Medicine, experts from different disciplines share their experience and summarize new research directed at maintaining and improving function, independence and quality of life in individuals with CP.
A steady supply of its favorite food helps a deadly bacterium thrive in the lungs of people with cystic fibrosis, according to a new study by Columbia researchers.
Characterized by repetitive movements or vocalizations known as tics, Tourette Syndrome is a neurodevelopmental disorder that plagues many adolescents. A study conducted by Yale researchers has trained adolescents with Tourette Syndrome to control their tics through an imaging technique that allows patients to monitor the function of their own brain in real time.
New data showed that term, breastfed infants fed activated Bifidobacterium longum subsp. infantis EVC001 (B. infantis EVC001) experience improved metabolism of protein-bound glycans from human milk, compared to matched controls. Not only do these new data provide greater mechanistic understanding of how B. infantis selectively utilizes the glycans from human milk as growth substrate but may also provide a basis for facilitating B. infantis colonization in formula fed infants via utilization of bovine derived N-glycans.
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If the current trend in diagnostic practices holds, the definition of autism may get too blurry to be meaningful, a Canadian research team finds.