Researchers captured and comparted hi-res images of ribosome structures from sensitive and resistant bacteria and report that a water molecule needed for antibiotic binding was not present in the ribosomes from the drug-resistant bugs.
Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have developed a method named D2O-probed CANcer Susceptibility Test Ramanometry (D2O-CANST-R) to see, at single-cell/organelle level, how pharmaceuticals induce cancer cell death and how cancer cells adapt.
Summary Researchers at Osaka City University use quantum superposition states and Bayesian inference to create a quantum algorithm, easily executable on quantum computers, that accurately and directly calculates energy differences between the electronic ground and excited spin states of molecular systems in polynomial time.
Scientists have discovered a molecule that can selectively kill cells of a hard-to-treat subtype of breast cancer, which could lead to a new therapy.
Kanazawa University scientists use computer simulations of charged molecules to help improve the accuracy of mass spectrometers. By understanding the collisions between ions that reduce excess charges, this work may lead to more sensitive radiocarbon dating and medical testing.
'What goes in, must come out' is a familiar refrain. It is especially pertinent to the challenges facing UBC researchers who are investigating methods to remove chemicals and pharmaceuticals from public water systems. Cleaning products, organic dyes and pharmaceuticals are finding their ways into water bodies with wide-ranging negative implications to health and the environment, explains Dr. Mohammad Arjmand, an assistant professor of mechanical engineering at UBC Okanagan.
A new method to synthesize vaccines safely and quickly should see much faster pre-clinical testing to pursue strategies to combat novel pathogens, something the COVID pandemic has shown is necessary.
Naltrexone, used either alone or together with disulfiram or acamprosate, is associated with a decreased risk of hospitalization due to alcohol use disorder (AUD) when compared with non-use of AUD drugs, a new register-based study shows.
A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.
The newly published review 'Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood' describes the current status of assays for PINP and β-CTX in blood, as well as the plans for and ongoing progress towards the achievement of harmonization or standardization of commercial assays for these reference markers.