In a small, early phase trial, a high percentage of patients who had exhausted most traditional treatments for chronic lymphocytic leukemia saw their tumors shrink or even disappear after an infusion of a highly targeted, experimental CAR T-cell immunotherapy developed at Seattle's Fred Hutchinson Cancer Research Center.
Researchers are reporting the highest and most sustained levels to date of an essential blood-clotting factor in patients with the inherited bleeding disorder hemophilia B. After receiving a single dose of an experimental gene therapy in a clinical trial, patients with hemophilia produced near-normal levels of clotting factor IX, allowing them to stop clotting factor infusions and to pursue normal activities of daily life without disabling bleeding episodes.
A Norwegian study shows that saturated fat actually could be good for you. The quality of the food, whether it's highly processed or not, could have a larger impact on your health.
Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives.
Academics at Swansea University have carried out a dose-response analysis which suggests that pregnant women who take a specific type of antidepressant in early pregnancy have a small but significantly greater risk of having babies with major congenital anomalies (sometimes referred to as birth defects) or stillbirths compared with those who did not take these antidepressants.
Scientists have developed a highly sensitive sensor to detect tiny changes in strong magnetic fields. The sensor may find widespread use in medicine and other areas.
Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.
Scientists have identified the cluster of genes responsible for reproductive traits in the Primula flower, first noted as important by Charles Darwin more than 150 years ago.
The 'reproducibility crisis' in biomedical research has led to questions about the scientific rigor in animal research, and thus the ethical justification of animal experiments. In research publishing in the open-access journals PLOS Biology and PLOS ONE on Dec. 2, 2016, researchers from the University of Bern have assessed scientific rigor in animal experimentation in Switzerland. The study, commissioned by the Swiss Federal Food Safety and Veterinary Office, found widespread deficiencies in the reporting of experimental methodology.
Coastal Indigenous people eat on average 15 times more seafood per person than non-Indigenous people in the same country, according to new research from the University of British Columbia. The findings highlight the need to consider food sovereignty and cultural identity as part of fisheries policy and Indigenous human rights.