Irrigation for agriculture is the largest use of fresh water around the globe, but precise records and maps of when and where water is applied by farmers are difficult to locate. Now a team of researchers has discovered how to track water used in agriculture.
An international team of scientists, led by structural biologists at Van Andel Research Institute, has shed new light on a critical step in DNA replication, offering fresh insights into a fundamental process of life and driver of many different diseases, including cancer.
An older Neandertal from about 50,000 years ago, who had suffered multiple injuries and other degenerations, became deaf and must have relied on the help of others to avoid prey and survive well into his 40s, indicates a new analysis published Oct. 20 in the online journal PLoS ONE.
Figuring out how accurate replication works at the level of individual molecules and atoms is one of the great achievements of modern science. The journey of investigators is not yet done, however. A major unsolved part of the puzzle is understanding how the entire process of copying the genome begins. In new research, insight into how the two stands of the double helix separate in the earliest stages of replication is becoming clear.
A University of Colorado Cancer Center study published today in the journal Molecular Cancer Therapeutics finds a genetic change called ALK-fusion in a patient sample of a melanoma subtype called mucosal melanoma. When researchers treated a tumor grown from this sample with the drugs crizotinib and ceritinib -- both FDA approved to treat ALK-positive lung cancer -- the tumor responded dramatically.
An Emory/Yonsei team developed a new method for generating endothelial cells, which make up the lining of blood vessels, from human iPSCs. When endothelial cells are surrounded by a supportive gel and implanted into mice with damaged blood vessels, they become part of the animals' blood vessels, surviving for more than 10 months.
Northwestern Medicine scientists have revealed how oxidative stress explains a common herbicide's link to risk of Parkinson's disease.
As part of the long effort to improve treatment of tuberculosis (TB), microbiologists led by Yasu Morita at the University of Massachusetts Amherst report that they have for the first time characterized a protein involved in making a glycolipid compound found in the TB cell wall, which is critical for the disease-causing Mycobacterium to become infectious.
A new species of bird from the heart of Peru remained undetected for years until researchers identified it by its unique song.
As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells. In a new study, University of Wisconsin-Madison researchers map out the molecular events that direct cells' energy metabolism down the cancerous path. Their findings could lead to ways to interrupt the process.