Mule deer navigate in spring and fall mostly by using their knowledge of past migration routes and seasonal ranges.
Salk Institute researchers have developed a new tool -- dubbed SATI -- to edit the mouse genome, enabling the team to target a broad range of mutations and cell types. The new genome-editing technology could be expanded for use in a broad range of gene mutation conditions such as Huntington's disease and the rare premature aging syndrome, progeria.
In 'Invisible Designers: Brain Evolution Through the Lens of Parasite Manipulation,' published in the September 2019 issue of The Quarterly Review of Biology, Marco Del Giudice explores an overlooked aspect of the relationship between parasites and their hosts by systematically discussing the ways in which parasitic behavior manipulation may encourage the evolution of mechanisms in the host's nervous and endocrine systems.
Caltech researchers identify the neural processes that make some memories fade rapidly while other memories persist over time.
Salk researchers discover that star-shaped cells called astrocytes help the brain establish long-lasting memories. The work could inform therapies for disorders in which long-term memory is impaired, such as traumatic brain injury or dementia.
Scientists find that black carbon is a good tracer to separate cooking organic aerosol from traffic-related organic aerosol.
As public health officials worry about the emergence of antibiotic-resistant gonorrhea, an MUSC researcher is tracing how antibiotics bind to a gonococcal protein, information that can help lead to new antimicrobials.
There are only two northern white rhinos left worldwide, both of them female. Saving this representative of megafauna from extinction seems impossible under these circumstances, yet an international consortium of scientists and conservationists just completed a procedure that could enable assisted reproduction techniques to do just that. On August 22, 2019, a team of veterinarians successfully harvested eggs from the two females who live in Ol Pejeta Conservancy in Kenya.
A team of scientists from MIPT and IBCh RAS studied one hereditary genetic mutation to discover general molecular mechanisms that may lead both to early onset of Alzheimer's disease and to the form of the disease caused by age-related changes in human body. Understanding these mechanisms is necessary for developing new targeted treatments for this neurodegenerative disease that is becoming ever more widespread across the developed countries' aging populations.
Targeted protein degradation (TPD) is a new paradigm in drug discovery that could lead to the development of new medicines to treat diseases such as cancer more effectively. A recent study by researchers at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences reveals global and drug-specific cellular effectors needed for TPD. The results have now been published in the scientific journal Molecular Cell.