According to the Centers for Disease Control and Prevention, approximately 735,000 Americans experience a heart attack each year. Opening a blocked coronary artery to restore blood flow to the heart prevents sudden cardiac death. However, doing so also triggers cardiac damage through oxidative stress and inflammation, which eventually can lead to heart failure. Researchers at the University of Missouri School of Medicine have identified a protein that can be targeted to decrease post-heart attack injury and prevent heart failure in a mouse model.
- Journal of Biological Chemistry
- US Department of Veterans Affairs Office of Research and Development-Biomedical Laboratory Research and Development Service Award, NIH/National Institute of Allergy and Infectious Diseases