USC scientists report a time-keeping mechanism in liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted.
In an article published in Endocrine Reviews, Brazilian professors discuss the general criteria to be considered when prescribing the pineal hormone as a health supplement. The guidelines will help health professionals to analyze, understand and interpret the effects of melatonin.
A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.
Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. Through this review, the researchers aimed to review the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.
Dopamine has a reputation as the key player in the brain's reward circuits, making us seek out pleasurable experiences, but growing evidence points to a multipronged role for the neurotransmitter. In particular, dopamine may also reinforce avoidance of painful experiences. UC Berkeley researchers have now mapped dopamine neurons in the brain with fiber photometry and discovered two parallel dopamine circuits driving attractive and aversive reinforcement learning and motivation.
You probably overestimate just how far someone can push you before you reach your tipping point, new research suggests. A new study tilted people backwards in a device and asked them at what point they thought they would fall if they weren't supported. Most people would have fallen long before they thought they would.
Researchers have discovered what might be an effective strategy to prevent and combat cognitive dysfunction in obese individuals. They are the first to examine the modulatory role of an exercise-induced protein in the brain that promotes neuron survival and used high-intensity interval exercise (HIIE) in obese and normal-weight subjects. Obesity reduces the expression of this protein and lower levels are associated with Alzheimer's, Parkinson's and obesity. HIIE upregulated this protein in the obese subjects compared to normal-weight subjects.
The plant hormone jasmonic acid also performs a function that was previously unknown. It ensures that the leaf pores close when leaves are injured. For the plant, this could be an emergency signal.
Regenerative Medicine is delighted to publish open access original research demonstrating the first virus- and oncogene-free induced pluripotent stem cell (iPSC) technology to produce safer pluripotent stem cells from cord blood and peripheral blood.
Patients with lymph node ratio greater than 10 percent had about 2.5 times greater risk of cancer recurrence and 2.7 times greater risk of death than patients with LNR below 10 percent.