New research suggests that rising childhood obesity rates are causing more adolescents to develop a debilitating hip disease requiring urgent surgery.
With the help of a free phone app, low-income obese patients with signs of cardiovascular risk lost a clinically meaningful amount of weight, finds new research from Duke University. The study is among the first to report successful weight loss within a low-income population -- a group that suffers from skyrocketing rates of obesity but has proven hard to treat, said lead author Gary Bennett.
Despite the legalization of marijuana on Oct. 17, the long-term effects of smoked cannabis on lung health are unknown and more research is needed, argue authors in a commentary in CMAJ.
Information provided to new parents in hospital about how to alleviate pain for their babies during vaccination resulted in more frequent use of pain interventions at future infant vaccinations, reports a study published in CMAJ.
In a randomized, placebo-controlled study, researchers from Israel have shown that cannabis can produce clinical remission in up to 65 percent of individuals after eight weeks of treatment, but that this improvement does not appear to result from a dampening down of the underlying inflammatory process.
Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congress in Munich, has highlighted the existence of barriers to the inclusion of 12 to 25-year-olds in both adult and paediatric early phase clinical trials, suggesting a need for more tailored approaches to give this patient population better access to therapeutic innovation.
Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis (AS), a chronic inflammatory disease characterized by back pain and sacroiliac-joint damage, may have another treatment option in the biologic drug ixekizumab.
Mount Sinai Scientists developed a novel way to barcode and track different CRISPRs by utilizing synthetic proteins built from combinations of smaller proteins, called epitopes. By being able to mark each CRISPR with a unique identifier, the protein barcodes, or Pro-Codes for short, enable hundreds of CRISPRs to be used together to knockout a multitude of genes.
In a commentary published by the American Journal of Kidney Diseases, Sun-Young Ahn, M.D., and Marva Moxey-Mims, M.D., explain that pediatric chronic kidney disease can contribute to growth failure, developmental and neurocognitive defects, and impaired cardiovascular health.
A new Florida State University College of Medicine study in mice produced results that suggest nicotine exposure in men could lead to cognitive deficits in their children and grandchildren. Further studies will be required to know if the same outcomes seen in mice would apply to humans.